Inhibiting corneal neovascularization by sustainably releasing anti-VEGF and anti-inflammation drugs from silica-thermogel nanohybrids

N Lyu, Y Zhao, J Xiang, X Fan, C Huang, X Sun… - Materials Science and …, 2021 - Elsevier
Corneal neovascularization (CNV) is one of the main factors that induce blindness
worldwide. To effectively inhibit CNV, a novel nanohybrid has been developed by …

A facile method to construct ZIF-8 MOFs on contact lens for high antibiotics loading and self-defensive release

Y Shao, H Suo, S Wang, Y Peng, X Chu, Z Long… - Chemical Engineering …, 2024 - Elsevier
Eye trauma, ophthalmic surgery and contact lens (CL) wearing cause corneal infection and
bacterial biofilms formation, which further lead to corneal ulcer and perforation. In view of the …

Development of dexamethasone loaded nanomicelles using a 3D printed microfluidic device for ocular drug delivery applications

MB Kulkarni, K Velmurugan, J Nirmal, S Goel - Sensors and Actuators A …, 2023 - Elsevier
Evidently, nanomicelles serve as an outstanding pharmaceutical carrier due to their small
size, capability to reduce the associated side effects and drug degradation, and improved …

Lipid-based nanoparticulate systems for the ocular delivery of bioactives with anti-inflammatory properties

R Ana, J Fonseca, J Karczewski, AM Silva… - International Journal of …, 2022 - mdpi.com
The complexity of the eye structure and its physiology turned ocular drug administration into
one of the most challenging topics in the pharmaceutical field. Ocular inflammation is one of …

How liposomes pave the way for ocular drug delivery after topical administration

N Tasharrofi, M Nourozi, A Marzban - Journal of Drug Delivery Science and …, 2022 - Elsevier
The eye is one of the most specialized organs in the body; one of its flawless functions is
vigorously controlling the foreign materials' entrance to the eye. On the other hand, this …

Biopolymer-based nano-formulations for mitigation of ocular infections: a review

D Karati, S Mukherjee, S Singh, BG Prajapati, B Basu - Polymer Bulletin, 2024 - Springer
Ocular infirmities significantly influence a person's routine process by impairing vision to the
point of blindness. Effective ocular drug administration with significant bioavailability is …

Current advances in nano-based and polymeric stimuli-responsive drug delivery targeting the ocular microenvironment: a review and envisaged future perspectives

SBK Dludla, LT Mashabela, B Ng'andwe, PA Makoni… - Polymers, 2022 - mdpi.com
Optimal vision remains one of the most essential elements of the sensory system
continuously threatened by many ocular pathologies. Various pharmacological agents …

Nanoparticle-mediated gene therapy as a novel strategy for the treatment of retinoblastoma

M Mandal, I Banerjee, M Mandal - Colloids and Surfaces B: Biointerfaces, 2022 - Elsevier
Over the last two decades, nanoparticulate delivery systems have revolutionized cancer
treatment by achieving target-specific delivery, enhanced bioavailability, and improved …

Quantum dots as a good carriers of unsymmetrical bisacridines for modulating cellular uptake and the biological response in lung and colon cancer cells

J Pilch, P Kowalik, P Bujak, AM Nowicka, E Augustin - Nanomaterials, 2021 - mdpi.com
Nanotechnology-based drug delivery provides a promising area for improving the efficacy of
cancer treatments. Therefore, we investigate the potential of using quantum dots (QDs) as …

Nanomaterials in the diagnosis and treatment of ophthalmic diseases

Y Ma, Z Zhang, Y Yu, X Wang, S Liu, B Sun, Z Cai… - Nano Today, 2024 - Elsevier
The complexity of the human eye structure poses challenges in the diagnosis and treatment
of ocular diseases, especially the low efficiency of ocular drug delivery. With the continuous …