Tobacco Smoking and Liver Cancer Risk: Potential Avenues for Carcinogenesis
D Jain, P Chaudhary, N Varshney… - Journal of …, 2021 - Wiley Online Library
Smoking a cigarette generates over 4000 chemicals that have a deleterious impact on each
part of the human body. It produces three main severe effects on the liver organ: oncogenic …
part of the human body. It produces three main severe effects on the liver organ: oncogenic …
Modulation of immune responses using adjuvants to facilitate therapeutic vaccination
V Schijns, A Fernández‐Tejada… - Immunological …, 2020 - Wiley Online Library
Therapeutic vaccination offers great promise as an intervention for a diversity of infectious
and non‐infectious conditions. Given that most chronic health conditions are thought to have …
and non‐infectious conditions. Given that most chronic health conditions are thought to have …
[HTML][HTML] Novel Immunoinformatics Approaches to Design Multi-epitope Subunit Vaccine for Malaria by Investigating Anopheles Salivary Protein
Malaria fever has been pervasive for quite a while in tropical developing regions causing
high morbidity and mortality. The causal organism is a protozoan parasite of genus …
high morbidity and mortality. The causal organism is a protozoan parasite of genus …
Designing cell lines for viral vaccine production: Where do we stand?
Y Genzel - Biotechnology journal, 2015 - Wiley Online Library
Established animal cells, such as Vero, Madin Darby canine kidney (MDCK) or chicken
embryo fibroblasts (CEFs), are still the main cell lines used for viral vaccine production …
embryo fibroblasts (CEFs), are still the main cell lines used for viral vaccine production …
Development of vaccines to treat opioid use disorders and reduce incidence of overdose
M Pravetoni, SD Comer - Neuropharmacology, 2019 - Elsevier
Vaccines offer a promising therapeutic strategy to treat substance use disorders (SUD).
Vaccines have shown extensive preclinical proof of selectivity, safety, and efficacy against …
Vaccines have shown extensive preclinical proof of selectivity, safety, and efficacy against …
Nicotine and tobacco as substances of abuse in children and adolescents
LM Siqueira, SA Ryan, PK Gonzalez, SW Patrick… - …, 2017 - publications.aap.org
Nicotine is the primary pharmacologic component of tobacco, and users of tobacco products
seek out its effects. The highly addictive nature of nicotine is responsible for its widespread …
seek out its effects. The highly addictive nature of nicotine is responsible for its widespread …
[HTML][HTML] Designs of antigen structure and composition for improved protein-based vaccine efficacy
Today, vaccinologists have come to understand that the hallmark of any protective immune
response is the antigen. However, it is not the whole antigen that dictates the immune …
response is the antigen. However, it is not the whole antigen that dictates the immune …
[HTML][HTML] Nanoparticle delivery systems for substance use disorder
V Kasina, RJ Mownn, R Bahal, GC Sartor - Neuropsychopharmacology, 2022 - nature.com
Innovative breakthroughs in nanotechnology are having a substantial impact in healthcare,
especially for brain diseases where effective therapeutic delivery systems are desperately …
especially for brain diseases where effective therapeutic delivery systems are desperately …
Adjuvants for vaccines to drugs of abuse and addiction
Immunotherapeutic vaccines to drugs of abuse, including nicotine, cocaine, heroin,
oxycodone, methamphetamine, and others are being developed. The theoretical basis of …
oxycodone, methamphetamine, and others are being developed. The theoretical basis of …
[HTML][HTML] An immunoinformatic approach driven by experimental proteomics: in silico design of a subunit candidate vaccine targeting secretory proteins of Leishmania …
Background Visceral leishmaniasis (VL) caused by dimorphic Leishmania species is a
parasitic disease with high socioeconomic burden in endemic areas worldwide. Sustaining …
parasitic disease with high socioeconomic burden in endemic areas worldwide. Sustaining …