The urogenital tract is a complex environment composed of many different types of epithelial
tissues and innate immune cells that sample the surrounding milieu. As a host-adapted …

Neisseria gonorrhoeae (also known as gonococcus) has been causing gonorrhoea in
humans since ancient Egyptian times. Today, global gonorrhoea infections are rising at an …

Women acquire human immunodeficiency virus (HIV) mainly through sexual intercourse.
However, low transmission rates per sexual act indicate that local immune mechanisms …

Pathogenesis of Neisseria gonorrhoeae in the female reproduc... : Current Opinion in
Hematology Pathogenesis of Neisseria gonorrhoeae in the female reproductive tract …

Pseudomonas aeruginosa is an opportunistic pathogen causing severe infections often
characterized by robust neutrophilic infiltration. Neutrophils provide the first line of defense …

Infections with bacterial pathogens often results in the initiation of programmed cell death as
part of the host innate immune defense, or as a bacterial virulence strategy. Induction of host …

The mucosal inflammatory response to Neisseria gonorrhoeae (Gc) is characterized by
recruitment of neutrophils to the site of infection. Gc survives exposure to neutrophils by …

Neutrophils, as innate effector cells, play an essential role in the containment and
elimination of pathogens. Among the main neutrophil mechanisms use for these processes …

Neutrophils are the most abundant circulating innate immune cells and comprise the first
immune defense line, as they are the most rapidly recruited cells at sites of infection or …

Neisseria gonorrhoeae initiates a strong local immune response that is characterized by
copious recruitment of neutrophils to the site of infection. Neutrophils neutralize microbes by …