Phase-field modeling of individual and collective cell migration

A Moure, H Gomez - Archives of Computational Methods in Engineering, 2021 - Springer
Cell motion is crucial in human health and development. Cells may migrate individually or in
highly coordinated groups. Cell motion results from complex intra-and extra-cellular …

Finite element methods for surface PDEs

G Dziuk, CM Elliott - Acta Numerica, 2013 - cambridge.org
In this article we consider finite element methods for approximating the solution of partial
differential equations on surfaces. We focus on surface finite elements on triangulated …

Virtual Cell: computational tools for modeling in cell biology

DC Resasco, F Gao, F Morgan, IL Novak… - … Systems Biology and …, 2012 - Wiley Online Library
Abstract The Virtual Cell (VCell) is a general computational framework for modeling
physicochemical and electrophysiological processes in living cells. Developed by the …

[HTML][HTML] Solving PDEs in complex geometries: a diffuse domain approach

X Li, J Lowengrub, A Rätz, A Voigt - … in mathematical sciences, 2009 - ncbi.nlm.nih.gov
We extend previous work and present a general approach for solving partial differential
equations in complex, stationary, or moving geometries with Dirichlet, Neumann, and Robin …

Virtual Cell modelling and simulation software environment

II Moraru, JC Schaff, BM Slepchenko, ML Blinov… - IET systems biology, 2008 - IET
The Virtual Cell (VCell; http://vcell. org/) is a problem solving environment, built on a central
database, for analysis, modelling and simulation of cell biological processes. VCell …

Finite element analysis for a coupled bulk–surface partial differential equation

CM Elliott, T Ranner - IMA Journal of Numerical Analysis, 2013 - ieeexplore.ieee.org
In this paper, we define a new finite element method for numerically approximating the
solution of a partial differential equation in a bulk region coupled with a surface partial …

Spatial modeling of cell signaling networks

AE Cowan, II Moraru, JC Schaff, BM Slepchenko… - Methods in cell …, 2012 - Elsevier
The shape of a cell, the sizes of subcellular compartments, and the spatial distribution of
molecules within the cytoplasm can all control how molecules interact to produce a cellular …

A coupled bulk-surface model for cell polarisation

D Cusseddu, L Edelstein-Keshet, JA Mackenzie… - Journal of theoretical …, 2019 - Elsevier
Several cellular activities, such as directed cell migration, are coordinated by an intricate
network of biochemical reactions which lead to a polarised state of the cell, in which cellular …

Scattered data interpolation on embedded submanifolds with restricted positive definite kernels: Sobolev error estimates

E Fuselier, GB Wright - SIAM Journal on Numerical Analysis, 2012 - SIAM
In this paper we present error estimates for kernel interpolation at scattered sites on
manifolds. The kernels we consider will be obtained by the restriction of positive definite …

Diffusion on a sphere with localized traps: Mean first passage time, eigenvalue asymptotics, and Fekete points

D Coombs, R Straube, M Ward - SIAM Journal on Applied Mathematics, 2009 - SIAM
A common scenario in cellular signal transduction is that a diffusing surface-bound molecule
must arrive at a localized signaling region on the cell membrane before the signaling …