Nociplastic pain is a recently distinguished type of pain, distinct from neuropathic and
nociceptive pain, and is well described in the literature. It is often mistaken for central …

Migraine is a serious central nervous system disease with a high incidence rate. Its
pathogenesis is very complex, which brings great difficulties for clinical treatment. Recently …

The COVID-19 pandemic caused by SARS-CoV-2 has triggered a consequential public
health crisis of post-acute sequelae of COVID-19 (PASC), sometimes referred to as long …

PET/MRI has been reported to be promising in the diagnosis and evaluation of infection and
inflammation including brain disorders, bone and soft tissue infections and inflammations …

Background Chronic pain involves communication between neural and immune systems.
Recent data suggest localization of glial (brain immune cells) activation to the sensorimotor …

Persistence of low back pain is thought to be associated with different underlying pain
mechanisms, including ongoing nociceptive input and central sensitisation. We …

Understanding the mechanisms that underpin the transition from acute to chronic pain is
critical for the development of more effective and targeted treatments. There is growing …

Pain is an important innate defense mechanism that can dramatically alter a person's quality
of life. Understanding the microbiological and physiological effects of pain may be important …

Objectives To evaluate the association between low back pain (LBP) and painful
temporomandibular disorders (TMDs). Methods Systematic review of observational studies …

Objective In patients with fibromyalgia (FM), the brain shows altered structure and functional
connectivity, but the mechanisms underlying these changes remain unclear. This study …