Alzheimer's disease's pathophysiology is still a conundrum. Growing number of evidences
have elucidated the involvement of oxidative stress in the pathology of AD rendering it a …

Microglia are the resident immune cells of the central nervous system that guarantee
immune surveillance and exert also a modulating role on neuronal synaptic development …

Background and Objectives We assessed whether novelty-related fMRI activity in medial
temporal lobe regions and the precuneus follows an inverted U-shaped pattern across the …

Many countries currently invest in technologies and data infrastructures to foster precision
medicine (PM), which is hoped to better tailor disease treatment and prevention to individual …

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the
cardinal features of tremor, bradykinesia, rigidity, and postural instability, in addition to other …

Background Imbalanced synaptic transmission appears to be an early driver in Alzheimer's
disease (AD) leading to brain network alterations. Early detection of altered synaptic …

Microglia are important phagocytes of the central nervous system (CNS). They play an
important role in protecting the CNS by clearing necrotic tissue and apoptotic cells in many …

Many risk factors have been identified that predict future progression to Alzheimer's disease
(AD). However, clear links have yet to be made between these risk factors and how they …

Throughout the nervous system, the convergence of two or more presynaptic inputs on a
target cell is commonly observed. The question we ask here is to what extent converging …

This systematic review aimed to evaluate previous studies which used near-infrared
spectroscopy (NIRS) in dementia given its suitability as a diagnostic and investigative tool in …