Schiff bases in medicinal chemistry: a patent review (2010-2015)
A Hameed, M Al-Rashida, M Uroos… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Schiff bases are synthetically accessible and structurally diverse compounds,
typically obtained by facile condensation between an aldehyde, or a ketone with primary …
typically obtained by facile condensation between an aldehyde, or a ketone with primary …
Hydrazone comprising compounds as promising anti-infective agents: Chemistry and structure-property relationship
Despite the adverse effects of microbial hazards on public health, major pharmaceutical
firms have left the field of anti-infective development and a dramatic reduction in the number …
firms have left the field of anti-infective development and a dramatic reduction in the number …
Investigation on corrosion protection behavior and adsorption of carbohydrazide-pyrazole compounds on mild steel in 15% HCl solution: Electrochemical and …
The behavior of synthesized (E)-5-amino-3-(4-methoxyphenyl)-N′-(1-(4-methoxyphenyl)
ethylidene)-1H-pyrazole-4-carbohydrazide [AMPC] and (E)-5-amino-N′-(4 …
ethylidene)-1H-pyrazole-4-carbohydrazide [AMPC] and (E)-5-amino-N′-(4 …
The use of hydrazones for biomedical applications
J Wahbeh, S Milkowski - SLAS TECHNOLOGY: Translating …, 2019 - journals.sagepub.com
The use of hydrazones presents an opportunity for enhancing drug delivery through site-
specific drug release, including areas such as tumor tissue or thrombosis. Many researchers …
specific drug release, including areas such as tumor tissue or thrombosis. Many researchers …
Synthesis, characterization, and comprehensive computational analysis of aromatic hydrazone compounds: Unveiling quantum parameters, evaluating antioxidant …
This study presents a synergistic approach encompassing experimental synthesis,
computational analysis, and antioxidant activity evaluation of two aromatic hydrazone …
computational analysis, and antioxidant activity evaluation of two aromatic hydrazone …
Synthesis, characterizations, antitumor and antimicrobial evaluations of novel Mn (II) and Cu (II) complexes with NNN-tridentate s-Triazine-Schiff base ligand
EM Fathalla, MAM Abu-Youssef, MM Sharaf… - Inorganica Chimica …, 2023 - Elsevier
The new s-triazine hydrazone, 2, 4-bis (morpholin-4-yl)-6-[(E)-2-[1-(pyridin-2-yl) ethylidene]
hydrazin-1-yl]-1, 3, 5-triazine,(L) ligand was used to synthesize three new metal complexes …
hydrazin-1-yl]-1, 3, 5-triazine,(L) ligand was used to synthesize three new metal complexes …
2-(2-(2, 4-dioxopentan-3-ylidene) hydrazineyl) benzonitrile as novel inhibitor of receptor tyrosine kinase and PI3K/AKT/mTOR signaling pathway in glioblastoma
Nerve growth factor receptor (NGFR), a member of kinase protein, is emerging as an
important target for Glioblastoma (GBM) treatment. Overexpression of NGFR is observed in …
important target for Glioblastoma (GBM) treatment. Overexpression of NGFR is observed in …
Characterization of antimicrobial, antioxidant, and leishmanicidal activities of Schiff base derivatives of 4-aminoantipyrine
R Teran, R Guevara, J Mora, L Dobronski… - Molecules, 2019 - mdpi.com
Our main interest is the characterization of compounds to support the development of
alternatives to currently marketed drugs that are losing effectiveness due to the development …
alternatives to currently marketed drugs that are losing effectiveness due to the development …
Novel tetrazole and cyanamide derivatives as inhibitors of cyclooxygenase-2 enzyme: design, synthesis, anti-inflammatory evaluation, ulcerogenic liability and …
Nineteen new compounds containing tetrazole and/or cyanamide moiety have been
designed and synthesised. Their structures were confirmed using spectroscopic methods …
designed and synthesised. Their structures were confirmed using spectroscopic methods …
Recent research trends on bismuth compounds in cancer chemo-and radiotherapy
M Kowalik, J Masternak… - Current medicinal …, 2019 - ingentaconnect.com
Background: Application of coordination chemistry in nanotechnology is a rapidly
developing research field in medicine. Bismuth complexes have been widely used in …
developing research field in medicine. Bismuth complexes have been widely used in …