Antibiotic resistance: The challenges and some emerging strategies for tackling a global menace

D Chinemerem Nwobodo, MC Ugwu… - Journal of clinical …, 2022 - Wiley Online Library
Background Antibiotic resistance is currently the most serious global threat to the effective
treatment of bacterial infections. Antibiotic resistance has been established to adversely …

[HTML][HTML] Progress in alternative strategies to combat antimicrobial resistance: Focus on antibiotics

J Murugaiyan, PA Kumar, GS Rao, K Iskandar… - Antibiotics, 2022 - mdpi.com
Antibiotic resistance, and, in a broader perspective, antimicrobial resistance (AMR),
continues to evolve and spread beyond all boundaries. As a result, infectious diseases have …

Antimicrobial peptides, conventional antibiotics, and their synergistic utility for the treatment of drug‐resistant infections

Y Zhu, W Hao, X Wang, J Ouyang… - Medicinal Research …, 2022 - Wiley Online Library
Antimicrobial peptides (AMPs), also known as host defense peptides (HDPs), are important
effector immune defense molecules in multicellular organisms. AMPs exert their …

[HTML][HTML] Antimicrobial peptides—Mechanisms of action, antimicrobial effects and clinical applications

J Talapko, T Meštrović, M Juzbašić, M Tomas, S Erić… - Antibiotics, 2022 - mdpi.com
The growing emergence of antimicrobial resistance represents a global problem that not
only influences healthcare systems but also has grave implications for political and …

[HTML][HTML] Insights in the development and uses of alternatives to antibiotic growth promoters in poultry and swine production

MRT Rahman, I Fliss, E Biron - Antibiotics, 2022 - mdpi.com
The overuse and misuse of antibiotics has contributed to the rise and spread of multidrug-
resistant bacteria. To address this global public health threat, many countries have restricted …

[HTML][HTML] Antibacterial coatings for titanium implants: Recent trends and future perspectives

S Akshaya, PK Rowlo, A Dukle, AJ Nathanael - Antibiotics, 2022 - mdpi.com
Titanium and its alloys are widely used as implant materials for biomedical devices owing to
their high mechanical strength, biocompatibility, and corrosion resistance. However, there is …

[HTML][HTML] Antimicrobial mechanisms and clinical application prospects of antimicrobial peptides

X Li, S Zuo, B Wang, K Zhang, Y Wang - Molecules, 2022 - mdpi.com
Antimicrobial peptides are a type of small-molecule peptide that widely exist in nature and
are components of the innate immunity of almost all living things. They play an important role …

[HTML][HTML] Focus: antimicrobial resistance: antimicrobial peptides therapy: an emerging alternative for treating drug-resistant bacteria

IE Mba, EI Nweze - The Yale journal of biology and medicine, 2022 - ncbi.nlm.nih.gov
Microbial resistance to antibiotics is an ancient and dynamic issue that has brought a
situation reminiscent of the pre-antibiotic era to the limelight. Currently, antibiotic resistance …

[HTML][HTML] Bioactive compounds for human and planetary health

M Kussmann, DH Abe Cunha, S Berciano - Frontiers in Nutrition, 2023 - frontiersin.org
Bioactive compounds found in edible plants and foods are vital for human and planetary
health, yet their significance remains underappreciated. These natural bioactives, as part of …

[HTML][HTML] The use of antibody-antibiotic conjugates to fight bacterial infections

M Cavaco, MARB Castanho, V Neves - Frontiers in Microbiology, 2022 - frontiersin.org
The emergence of antimicrobial resistance (AMR) is rapidly increasing and it is one of the
significant twenty-first century's healthcare challenges. Unfortunately, the development of …