Background Septic encephalopathy is a severe brain dysfunction caused by systemic
inflammation in the absence of direct brain infection. Changes in cerebral blood flow …

Laser speckle flowmetry (LSF) is useful to assess noninvasively two-dimensional cerebral
blood flow (CBF) with high temporal and spatial resolution. The authors show that LSF can …

Although noninvasive, continuous monitoring of glucose concentration in blood and tissues
is one of the most challenging areas in medicine, a wide range of optical techniques has …

Background Early recanalization of occluded vessels in stroke is closely associated with
improved clinical outcome. Microbubble-enhanced sonothrombolysis is a promising therapy …

Background: This investigation aimed to: 1) develop a method to obtain reproducible laser
Doppler flow readings (LDFRs) at the gingiva of the maxillary front teeth; 2) evaluate …

Background Cerebral ischemic tolerance can be induced by a variety of noxious stimuli, but
no clinically applicable regimen for preconditioning has been described. Therefore, the …

Background Early recanalization of large cerebral vessels in ischemic stroke is associated
with improved clinical outcome, however persisting hypoperfusion leads to poor clinical …

The embolic MCA occlusion model in rats is used for recanalisation studies in acute stroke.
In addition to the determination of lesion size, the assessment of functional outcome may …

There are major differences in the outcome of focal cerebral ischemia between rat strains.
This study aimed to investigate whether inter-strain differences exist in the local cerebral …

Cortical spreading depression (CSD) is a temporary disruption of local ionic homeostasis
that propagates slowly across the cerebral cortex. Cortical spreading depression promotes …