A uridylate tract mediates efficient heterogeneous nuclear ribonucleoprotein C protein-RNA cross-linking and functionally substitutes for the downstream element of …
J Wilusz, T Shenk - Molecular and cellular biology, 1990 - Am Soc Microbiol
Every RNA added to an in vitro polyadenylation extract became stably associated with both
the heterogeneous nuclear ribonucleoprotein (hnRNP) A and C proteins, as assayed by …
the heterogeneous nuclear ribonucleoprotein (hnRNP) A and C proteins, as assayed by …
Poly (A) site cleavage in a HeLa nuclear extract is dependent on downstream sequences
RP Hart, MA McDevitt, JR Nevins - Cell, 1985 - cell.com
Efficient utilization of the early SV40 poly (A) site in vivo requires sequences between 5 bp
and 18 bp downstream of the cleavage site. We have used a HeLa nuclear extract to …
and 18 bp downstream of the cleavage site. We have used a HeLa nuclear extract to …
Regulation of poly (A) site use during mouse B-cell development involves a change in the binding of a general polyadenylation factor in a B-cell stage-specific manner
G Edwalds-Gilbert, C Milcarek - Molecular and Cellular Biology, 1995 - Am Soc Microbiol
During the development of mouse B cells there is a regulated shift from the production of
membrane to the secretion-specific forms of immunoglobulin (Ig) mRNA, which predominate …
membrane to the secretion-specific forms of immunoglobulin (Ig) mRNA, which predominate …
Multiple factors are required for specific RNA cleavage at a poly (A) addition site.
GM Gilmartin, MA McDevitt, JR Nevins - Genes & development, 1988 - genesdev.cshlp.org
An SP6 RNA containing the adenovirus 5 L3 poly (A) site is processed efficiently in a HeLa
cell nuclear extract to generate correct 3'termini. Accurate 3'processing has also been …
cell nuclear extract to generate correct 3'termini. Accurate 3'processing has also been …
Regulation of polyadenylation in human immunodeficiency virus (HIV): contributions of promoter proximity and upstream sequences.
J Cherrington, D Ganem - The EMBO journal, 1992 - embopress.org
Retroviruses synthesize a terminally redundant genomic RNA that contains canonical
polyadenylation signals at both ends. Production of this RNA requires that the 5′ copy of …
polyadenylation signals at both ends. Production of this RNA requires that the 5′ copy of …
Two proteins crosslinked to RNA containing the adenovirus L3 poly (A) site require the AAUAAA sequence for binding.
CL Moore, J Chen, J Whoriskey - The EMBO journal, 1988 - embopress.org
The major proteins crosslinked by UV light to RNA containing the adenovirus‐2 L3 poly (A)
site are species of 155, 68 and 38 kd mol. wt (p155, p68 and p38). Mutation of AAUAAA to …
site are species of 155, 68 and 38 kd mol. wt (p155, p68 and p38). Mutation of AAUAAA to …
Differential utilization of regulatory domains within the alpha 1 (I) collagen promoter in osseous and fibroblastic cells.
D Pavlin, AC Lichtler, A Bedalov, BE Kream… - The Journal of cell …, 1992 - rupress.org
Type I collagen is expressed in a variety of connective tissue cells and its transcriptional
regulation is highly complex because of the influence of numerous developmental …
regulation is highly complex because of the influence of numerous developmental …
Transcriptional regulation of a Bacillus subtilis dipeptide transport operon
FJ Slack, JR Mueller, MA Strauch… - Molecular …, 1991 - Wiley Online Library
The Bacillus subtilis dciA operon, which encodes a dipeptide transport system, was induced
rapidly by several conditions that caused the cells to enter stationary phase and initiate …
rapidly by several conditions that caused the cells to enter stationary phase and initiate …
Elements upstream of the AAUAAA within the human immunodeficiency virus polyadenylation signal are required for efficient polyadenylation in vitro
A Valsamakis, N Schek, JC Alwine - Molecular and cellular biology, 1992 - Taylor & Francis
Recent in vivo studies have identified specific sequences between 56 and 93 nucleotides
upstream of a polyadenylation [poly (A)] consensus sequence, AAUAAA, in human …
upstream of a polyadenylation [poly (A)] consensus sequence, AAUAAA, in human …
Sequence determinants of polyadenylation-mediated regulation
IV Slutskin, A Weinberger, E Segal - Genome research, 2019 - genome.cshlp.org
The cleavage and polyadenylation reaction is a crucial step in transcription termination and
pre-mRNA maturation in human cells. Despite extensive research, the encoding of …
pre-mRNA maturation in human cells. Despite extensive research, the encoding of …