Previous work from this laboratory has shown that glucocorticoids and (S p)-cAMPS, a cyclic
AMP analogue, stimulate the accumulation of angiotensinogen mRNA in isolated …

High affinity mouse HMG-I binding sites have been distinguished from other (A+ T)-rich
sequences using band competition assays. These sites have been found 3 'to the coding …

Region E3 encodes four major overlapping mRNAs with different splicing patterns. There
are two poly (A) sites, an upstream site called E3A and a downstream site called E3B. We …

Sequences downstream from the AATAAA motif in a number of cellular and viral
transcription units have been compared. A 12-bp conserved element was identified in …

The murine dihydrofolate reductase (DHFR) gene gives rise to multiple polyadenylated
mRNAs displaying heterogeneity in the length of the 3'untranslated region. These species …

Interferons (IFNs) induce the expression of a variety of cellular RNAs and inhibit phorbol
ester induction of other genes. Experiments reported here indicate that phorbol esters can …

Early/memory and plasma B-cell lines and fibroblasts were analyzed for their ability to use a
5′ proximal (variant) versus a 3′ distal (constant) poly (A) site, in the absence of a …

We have been interested in understanding more about the sequences that constitute the
polyomavirus late promoter. Our approach has been to target specific deletions to the viral …

Tumorigenic guinea pig cell lines with mutationally activated N-ras alleles also exhibited up-
regulated N-ras mRNA. Mutational activation and mRMA up-regulation were limited to …

Previous studies have shown that a sequence element downstream of the poly (A) addition
site is required for efficient cleavage in vivo. We tested a group of downstream element point …