Human African trypanosomiasis (sleeping sickness) is a parasitic infection that almost
invariably progresses to death unless treated. Human African trypanosomiasis caused …

Drug repurposing (also known as drug repositioning, drug reprofiling, indication expansion
or indication shift) involves establishing new medical uses for already known drugs …

The nitro group is considered to be a versatile and unique functional group in medicinal
chemistry. Despite a long history of use in therapeutics, the nitro group has toxicity issues …

Pathogenic animal trypanosomes affecting livestock have represented a major constraint to
agricultural development in Africa for centuries, and their negative economic impact is …

African trypanosomiasis is associated with Trypanosoma evansi, T. vivax, T. congolense,
and T. brucei pathogens in African animal trypanosomiasis (AAT) while T. b gambiense and …

With the incidence of sleeping sickness in decline and genuine progress being made
towards the WHO goal of eliminating sleeping sickness as a major public health concern …

This report presents the recommendations of the WHO Expert Committee responsible for
updating the WHO Model Lists of Essential Medicines.. The goal of the meeting was to …

Tritryps diseases are devastating parasitic neglected infections caused by Leishmania spp.,
Trypanosoma cruzi and Trypanosoma brucei subspecies. Together, these parasites affect …

Background Neuroblastoma (NB) is the most common cancer in infancy and most frequent
cause of death from extracranial solid tumors in children. Ornithine decarboxylase (ODC) …

Abstract The World Health Organization 'Ending the neglect to attain the Sustainable
Development Goals: A road map for neglected tropical diseases 2021–2030'outlines the …