Imaging lung perfusion

SR Hopkins, MO Wielpütz… - Journal of Applied …, 2012 - journals.physiology.org
From the first measurements of the distribution of pulmonary blood flow using radioactive
tracers by West and colleagues (J Clin Invest 40: 1–12, 1961) allowing gravitational …

Physiological imaging of the lung: single-photon-emission computed tomography (SPECT)

J Petersson, A Sánchez-Crespo… - Journal of applied …, 2007 - journals.physiology.org
Emission tomography provides three-dimensional, quantitative images of the distribution of
radiotracers used to mark physiological, metabolic, or pathological processes. Quantitative …

Vertical gradients in regional lung density and perfusion in the supine human lung: the Slinky effect

SR Hopkins, AC Henderson, DL Levin… - Journal of applied …, 2007 - journals.physiology.org
In vivo radioactive tracer and microsphere studies have differing conclusions as to the
magnitude of the gravitational effect on the distribution of pulmonary blood flow. We …

[HTML][HTML] Dual-layer dual-energy CT-derived pulmonary perfusion for the differentiation of acute pulmonary embolism and chronic thromboembolic pulmonary …

RJ Gertz, F Gerhardt, M Pienn, S Lennartz… - European …, 2023 - Springer
Objectives To evaluate dual-layer dual-energy computed tomography (dlDECT)–derived
pulmonary perfusion maps for differentiation between acute pulmonary embolism (PE) and …

[HTML][HTML] Imaging of pulmonary perfusion using subtraction CT angiography is feasible in clinical practice

D Grob, LJ Oostveen, M Prokop… - European …, 2019 - Springer
Subtraction computed tomography (SCT) is a technique that uses software-based motion
correction between an unenhanced and an enhanced CT scan for obtaining the iodine …

Multiple‐exchange‐time xenon polarization transfer contrast (MXTC) MRI: initial results in animals and healthy volunteers

I Dregely, IC Ruset, JF Mata, J Ketel… - Magnetic resonance …, 2012 - Wiley Online Library
Hyperpolarized xenon‐129 is a noninvasive contrast agent for lung MRI, which upon
inhalation dissolves in parenchymal structures, thus mirroring the gas‐exchange process for …

[HTML][HTML] Ventilation/perfusion relationships and gas exchange: measurement approaches

SR Hopkins - Comprehensive Physiology, 2020 - ncbi.nlm.nih.gov
Abstract Ventilation-perfusion (VA/Q) matching, the regional matching of the flow of fresh gas
to flow of deoxygenated capillary blood, is the most important mechanism affecting the …

Measuring lung water: Ex vivo validation of multi‐image gradient echo MRI

S Holverda, RJ Theilmann, RC Sá… - Journal of Magnetic …, 2011 - Wiley Online Library
Purpose: To validate a fast gradient echo sequence for rapid (9 s) quantitative imaging of
lung water. Materials and Methods: Eleven excised pig lungs were imaged with a fast GRE …

Regional lung blood flow and ventilation in upright humans studied with quantitative SPECT

J Petersson, M Rohdin, A Sánchez-Crespo… - Respiratory physiology …, 2009 - Elsevier
We used quantitative Single Photon Emission Computed Tomography (SPECT) to study the
effect of the upright posture on regional lung blood flow and ventilation. Nine (upright) plus …

Heart failure diagnostics based on ventilation/perfusion single photon emission computed tomography pattern and quantitative perfusion gradients

J Jögi, J Palmer, B Jonson, M Bajc - Nuclear medicine …, 2008 - journals.lww.com
Objective Left heart failure (LHF) is a common and frequently overlooked condition owing to
insufficient diagnostic methods. This can potentially delay onset of treatment. Our clinical …