The wound microbiota: microbial mechanisms of impaired wound healing and infection

A Uberoi, A McCready-Vangi, EA Grice - Nature Reviews Microbiology, 2024 - nature.com
The skin barrier protects the human body from invasion by exogenous and pathogenic
microorganisms. A breach in this barrier exposes the underlying tissue to microbial …

[HTML][HTML] Recent advances in 3D printed cellulose-based wound dressings: A review on in vitro and in vivo achievements

M Pita-Vilar, A Concheiro, C Alvarez-Lorenzo… - Carbohydrate …, 2023 - Elsevier
Chronic wounds, especially diabetic ulcers, pose a significant challenge in regenerative
medicine. Cellulose derivatives offer remarkable wound management properties, such as …

Moringa oleifera Leaf Extract Promotes Healing of Infected Wounds in Diabetic Rats: Evidence of Antimicrobial, Antioxidant and Proliferative Properties

AA Al-Ghanayem, MS Alhussaini, M Asad, B Joseph - Pharmaceuticals, 2022 - mdpi.com
Moringa oleifera is known to possess wound healing activity. The present study evaluated
the healing properties of methanolic extract of M. oleifera leaves in excision wounds infected …

Antibacterial, Anti-biofilm and pro-migratory effects of double layered hydrogels packaged with lactoferrin-DsiRNA-silver nanoparticles for chronic wound therapy

MAM Fathil, H Katas - Pharmaceutics, 2023 - mdpi.com
Antimicrobial resistance and biofilm formation in diabetic foot infections worsened during the
COVID-19 pandemic, resulting in more severe infections and increased amputations …

Antidiabetic plants for the treatment of type 2 diabetes mellitus and associated bacterial infections

MA Tienda-Vázquez, EM Melchor-Martínez… - Processes, 2023 - mdpi.com
Type 2 diabetes mellitus (T2DM) is the metabolic disease with the highest morbidity rates
worldwide. The condition is characterized by hyperglycemia, insulin resistance …

Bacterial profile and antimicrobial resistance patterns of infected diabetic foot ulcers in sub-Saharan Africa: a systematic review and meta-analysis

FW Wada, MF Mekonnen, ED Sawiso, S Kolato… - Scientific Reports, 2023 - nature.com
The number of diabetic foot ulcer patients is substantially increasing, with the rapidly rising
burden of diabetic mellitus in sub-Saharan Africa. The data on the regional prevalence of …

Evaluation and management of diabetes-related foot infections

NW Cortes-Penfield, DG Armstrong… - Clinical Infectious …, 2023 - academic.oup.com
Diabetes-related foot ulcers (DFUs) have a global prevalence of 6.3%, reaching 13% in
North America [1]. DFUs have a dismal prognosis, with 5-and 10-year survival rates of …

[HTML][HTML] What's old is new again: Insights into diabetic foot microbiome

AAH Rajab, WAH Hegazy - World Journal of Diabetes, 2023 - ncbi.nlm.nih.gov
Diabetes is a chronic disease that is considered one of the most stubborn global health
problems that continues to defy the efforts of scientists and physicians. The prevalence of …

Diabetic foot ulcer-a systematic review on relevant microbial etiology and antibiotic resistance in Asian countries

R Sultana, I Ahmed, S Saima, MT Salam… - Diabetes & Metabolic …, 2023 - Elsevier
Background and aims Diabetic foot ulcer (DFU) is one of the most common but uncontrolled
health issues of diabetic patients that needs more therapeutic considerations. This …

[HTML][HTML] Phage therapy for diabetic foot infection: a case series

MJ Young, LML Hall, M Merabishvilli, JP Pirnay… - Clinical Therapeutics, 2023 - Elsevier
Purpose Infected diabetic foot ulcers can be difficult to treat and, despite appropriate
antibiotic therapy, some diabetic foot infections (DFIs) require amputation. Bacteriophages …