Iron is a critical metal for several vital biological processes. Most of the body's iron is bound
to hemoglobin in erythrocytes. Iron from senescent red blood cells is recycled by …

Anemia of inflammation (AI), also known as anemia of chronic disease (ACD), is regarded
as the most frequent anemia in hospitalized and chronically ill patients. It is prevalent in …

Iron is an essential micronutrient for virtually all living cells. In infectious diseases, both
invading pathogens and mammalian cells including those of the immune system require iron …

Klebsiella pneumoniae is a Gram-negative opportunistic pathogen responsible for a variety
of community and hospital infections. Infections caused by carbapenem-resistant K …

Iron is a critical element for living cells in terrestrial life. Although iron metabolism is strictly
controlled in the body, disturbance of iron homeostasis under certain type of condition leads …

Background Severe coronavirus disease 2019 (COVID-19) is frequently associated with
hyperinflammation and hyperferritinemia. The latter is related to increased mortality in …

A greater understanding of hematopoietic stem cell (HSC) regulation is required for
dissecting protective versus detrimental immunity to pathogens that cause chronic infections …

200 billion red blood cells (RBCs) are produced every day, requiring more than 2× 10 15
iron atoms every second to maintain adequate erythropoiesis. These numbers translate into …

Genetic polymorphism varies among species and within genomes, and has important
implications for the evolution and conservation of species. The determinants of this variation …

Immunometabolism explores how the intracellular metabolic pathways in immune cells can
regulate their function under different micro-environmental and (patho-)-physiological …