BXD recombinant inbred (RI) lines represent a genetic reference population derived from a
cross between C57BL/6J mice (B6) and DBA/2J mice (D2), which through meiotic …

Could serial killing be addictive? Although scholars have discussed this possibility before, it
has not been rigorously tested. The present study closely examines Jeffrey Dahmer's …

Dopamine is a key neurotransmitter involved in physiological processes such as motor
control, motivation, reward, cognitive function, and maternal and reproductive behaviors …

This review examines the epigenetic of neurotrophin signaling in anxiety, affective disorders
and related symptoms associated with drug addiction, in particular alcoholism. It is first …

Background The Brain Reward Cascade (BRC) is an interaction of neurotransmitters and
their respective genes to control the amount of dopamine released within the brain. Any …

In Western countries, tobacco smoking is highly prevalent among patients co-infected with
HIV and hepatitis C virus (HCV). In the era of antiretrovirals and HCV cure, smoking-related …

Intense associative memories develop between drug-paired contextual cues and the drug
withdrawal associated aversive feeling. They have been suggested to contribute to the high …

Psychostimulant (methamphetamine, cocaine) use disorders have a genetic component that
remains mostly unknown. We conducted genome‐wide quantitative trait locus (QTL) …

Definition The inheritance of substance abuse, including opioid abuse, may be influenced
by genetic and non-genetic factors related to the environment, such as stress and …

Abstract Background Substance use disorders (SUDs) have been consistently shown to
exhibit moderate intergenerational continuity (1–3). While much research has examined …