Non-alcoholic fatty liver disease (NAFLD) and potential links to depression, anxiety, and chronic stress

S Shea, C Lionis, C Kite, L Atkinson, SS Chaggar… - Biomedicines, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) constitutes the most common liver disease
worldwide, and is frequently linked to the metabolic syndrome. The latter represents a …

“Mens Sana in Cute Sana”—a state of the art of mutual etiopathogenetic influence and relevant pathophysiological pathways between skin and mental disorders: an …

V Papa, F Li Pomi, F Borgia, S Genovese, G Pioggia… - Cells, 2023 - mdpi.com
The negative socioeconomic impact of mental health disorders and skin diseases has
increased in part due to the conflict between Russia and Ukraine, which has been a fertile …

NAc-VTA circuit underlies emotional stress-induced anxiety-like behavior in the three-chamber vicarious social defeat stress mouse model

G Qi, P Zhang, T Li, M Li, Q Zhang, F He… - Nature …, 2022 - nature.com
Emotional stress is considered a severe pathogenetic factor of psychiatric disorders.
However, the circuit mechanisms remain largely unclear. Using a three-chamber vicarious …

Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects

LS Kalinichenko, C Mühle, T Jia, F Anderheiden… - Molecular …, 2021 - nature.com
Mental disorders are highly comorbid and occur together with physical diseases, which are
often considered to arise from separate pathogenic pathways. We observed in alcohol …

Ten points to improve reproducibility and translation of animal research

R Spanagel - Frontiers in behavioral neuroscience, 2022 - frontiersin.org
Findings from animal experiments are often difficult to transfer to humans. In this perspective
article I discuss two questions. First, why are the results of animal experiments often so …

Nanoparticulate MgH2 ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress

Z Li, K Chen, Q Shao, H Lu, X Zhang, Y Pu… - Journal of …, 2023 - Springer
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous
system (CNS). Anxiety and depression are the most common psychiatric comorbidities of …

[HTML][HTML] Drug instrumentalization

CP Müller - Behavioural Brain Research, 2020 - Elsevier
Psychoactive drugs with addiction potential are widely used by people of virtually all cultures
in a non-addictive way. In order to understand this behaviour, its population penetrance, and …

Low income and schizophrenia risk: A narrative review

M Schneider, CP Müller, AK Knies - Behavioural brain research, 2022 - Elsevier
Despite decades of research, the precise etiology of schizophrenia is not fully understood.
Ample evidence indicates that the disorder derives from a complex interplay of genetic and …

Kratom use for depression/anxiety self-management: challenges during the COVID-19 pandemic–A case report

E Müller, T Hillemacher, CP Müller - Heliyon, 2021 - cell.com
Background Kratom is a psychoactive plant preparation originating from Southeast Asia. It
has been used as a recreational and performance drug in Southeast Asia, and is now …

Superoxide imbalance triggered by Val16Ala‐SOD2 polymorphism increases the risk of depression and self‐reported psychological stress in free‐living elderly …

IE da Cruz Jung, IBM da Cruz… - … Genetics & Genomic …, 2020 - Wiley Online Library
Background Oxidative stress and chronic inflammatory states triggered by a single‐
nucleotide polymorphism (SNP) in superoxide dismutase manganese‐dependent gene …