Microglia-mediated neuroinflammation and neuroplasticity after stroke
Stroke remains a major cause of long-term disability and mortality worldwide. The immune
system plays an important role in determining the condition of the brain following stroke. As …
system plays an important role in determining the condition of the brain following stroke. As …
Glial cells as therapeutic approaches in brain ischemia-reperfusion injury
IH Hernández, M Villa-González, G Martín, M Soto… - Cells, 2021 - mdpi.com
Ischemic stroke is the second cause of mortality and the first cause of long-term disability
constituting a serious socioeconomic burden worldwide. Approved treatments include …
constituting a serious socioeconomic burden worldwide. Approved treatments include …
Aloe-emodin prevents nerve injury and neuroinflammation caused by ischemic stroke via the PI3K/AKT/mTOR and NF-κB pathway
M Xian, J Cai, K Zheng, Q Liu, Y Liu, H Lin, S Liang… - Food & function, 2021 - pubs.rsc.org
Ischemic stroke (IS) caused by cerebral arterial occlusion is the leading cause of global
morbidity and mortality. Cellular oxidative stress and inflammation play a vital role in the …
morbidity and mortality. Cellular oxidative stress and inflammation play a vital role in the …
Neuroinflammation: a possible link between chronic vascular disorders and neurodegenerative diseases
Various age-related diseases involve systemic inflammation, ie a stereotyped series of acute
immune system responses, and aging itself is commonly associated with low-grade …
immune system responses, and aging itself is commonly associated with low-grade …
Minocycline improves autism-related behaviors by modulating microglia polarization in a mouse model of autism
Y Luo, K Lv, Z Du, D Zhang, M Chen, J Luo… - International …, 2023 - Elsevier
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder with few
pharmacological treatments. Minocycline, a tetracycline derivative that inhibits microglial …
pharmacological treatments. Minocycline, a tetracycline derivative that inhibits microglial …
Microglial phagocytosis and regulatory mechanisms after stroke
W Chen, Y Zhang, X Zhai, L Xie, Y Guo… - Journal of Cerebral …, 2022 - journals.sagepub.com
Stroke, including ischemic stroke and hemorrhagic stroke can cause massive neuronal
death and disruption of brain structure, which is followed by secondary inflammatory injury …
death and disruption of brain structure, which is followed by secondary inflammatory injury …
Ferulic acid alleviates retinal neovascularization by modulating microglia/macrophage polarization through the ROS/NF-κB axis
X Sun, L Ma, X Li, J Wang, Y Li, Z Huang - Frontiers in Immunology, 2022 - frontiersin.org
Inflammation plays a pivotal role in ischemia-induced retinal neovascularization. Targeting
microglia/macrophage-based neuroinflammation presents a promising therapeutic strategy …
microglia/macrophage-based neuroinflammation presents a promising therapeutic strategy …
Novel insight into cGAS-STING pathway in ischemic stroke: from pre-to post-disease
X Ma, D Xin, R She, D Liu, J Ge, Z Mei - Frontiers in Immunology, 2023 - frontiersin.org
Ischemic stroke, a primary cause of disability and the second leading cause of mortality, has
emerged as an urgent public health issue. Growing evidence suggests that the Cyclic GMP …
emerged as an urgent public health issue. Growing evidence suggests that the Cyclic GMP …
Melatonin regulates microglial polarization and protects against ischemic stroke-induced brain injury in mice
D Li, T He, Y Zhang, J Liu, H Zhao, D Wang… - Experimental …, 2023 - Elsevier
Ischemic stroke is a leading cause of mortality and morbidity worldwide, with
neuroinflammation playing a key role in its pathophysiology. Microglia, the primary immune …
neuroinflammation playing a key role in its pathophysiology. Microglia, the primary immune …
Ischemic stroke: From pathological mechanisms to neuroprotective strategies
Y Jiang, Z Liu, Y Liao, S Sun, Y Dai, Y Tang - Frontiers in Neurology, 2022 - frontiersin.org
Ischemic stroke (IS) has complex pathological mechanisms, and is extremely difficult to treat.
At present, the treatment of IS is mainly based on intravenous thrombolysis and mechanical …
At present, the treatment of IS is mainly based on intravenous thrombolysis and mechanical …