Introduction Because of the high mortality of invasive fungal infections (IFIs), appropriate
exposure to antifungals appears to be crucial for therapeutic efficacy and safety. Materials …

Antifungal therapy is a central component of patient management for acute and chronic
mycoses. Yet, treatment choices are restricted because of the sparse number of antifungal …

This review provides insight into the rapidly expanding field of metal-based antifungal
agents. In recent decades, the antibacterial resistance crisis has caused reflection on many …

The Candida genus comprises opportunistic fungi that can become pathogenic when the
immune system of the host fails. Candida albicans is the most important and prevalent …

The last few decades have seen an alarming rise in fungal infections, which currently
represent a global health threat. Despite extensive research towards the development of …

Fungal infections, such as candidiasis caused by Candida, pose a problem of growing
medical concern. In developed countries, the incidence of Candida infections is increasing …

Guidelines for the management of patients with invasive candidiasis and mucosal
candidiasis were prepared by an Expert Panel of the Infectious Diseases Society of America …

The introduction of new antifungal agents (eg, echinocandins, second-generation triazoles)
in the past decade has transformed the management of invasive mycoses to the point that …

Candida species are the most common cause of fungal infections. Candida species produce
infections that range from non—life-threatening mucocutaneous illnesses to invasive …

Morpholine is a versatile moiety, a privileged pharmacophore and an outstanding
heterocyclic motif with wide ranges of pharmacological activities due to different …