Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions
Polyunsaturated fatty acids (PUFAs) are structural components of membrane phospholipids,
and influence cellular function via effects on membrane properties, and also by acting as a …
and influence cellular function via effects on membrane properties, and also by acting as a …
Inflammation and tumor progression: signaling pathways and targeted intervention
H Zhao, L Wu, G Yan, Y Chen, M Zhou… - Signal transduction and …, 2021 - nature.com
Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …
either promotes or suppresses tumor progression, potentially displaying opposing effects on …
Inflammation after spinal cord injury: a review of the critical timeline of signaling cues and cellular infiltration
DJ Hellenbrand, CM Quinn, ZJ Piper… - Journal of …, 2021 - Springer
Traumatic spinal cord injury (SCI) is a devastating neurological condition that results in a
loss of motor and sensory function. Although extensive research to develop treatments for …
loss of motor and sensory function. Although extensive research to develop treatments for …
[HTML][HTML] Free fatty acid receptors in health and disease
Fatty acids are metabolized and synthesized as energy substrates during biological
responses. Long-and medium-chain fatty acids derived mainly from dietary triglycerides, and …
responses. Long-and medium-chain fatty acids derived mainly from dietary triglycerides, and …
Omega-3 and omega-6 polyunsaturated fatty acids: Dietary sources, metabolism, and significance—A review
RK Saini, YS Keum - Life sciences, 2018 - Elsevier
Abstract Linoleic acid (LA)(n− 6) and α-linolenic acid (ALA)(n− 3) are essential fatty acids
(EFAs) as they cannot be synthesized by humans or other higher animals. In the human …
(EFAs) as they cannot be synthesized by humans or other higher animals. In the human …
Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators
CN Serhan, BD Levy - The Journal of clinical investigation, 2018 - Am Soc Clin Investig
Countless times each day, the acute inflammatory response protects us from invading
microbes, injuries, and insults from within, as in surgery-induced tissue injury. These …
microbes, injuries, and insults from within, as in surgery-induced tissue injury. These …
The role of micronutrients in support of the immune response against viral infections
F Pecora, F Persico, A Argentiero, C Neglia, S Esposito - Nutrients, 2020 - mdpi.com
Viral infections are a leading cause of morbidity and mortality worldwide, and the importance
of public health practices including handwashing and vaccinations in reducing their spread …
of public health practices including handwashing and vaccinations in reducing their spread …
Pro-resolving lipid mediators: regulators of inflammation, metabolism and kidney function
Obesity, diabetes mellitus, hypertension and cardiovascular disease are risk factors for
chronic kidney disease (CKD) and kidney failure. Chronic, low-grade inflammation is …
chronic kidney disease (CKD) and kidney failure. Chronic, low-grade inflammation is …
Biomaterials: foreign bodies or tuners for the immune response?
E Mariani, G Lisignoli, RM Borzì… - International journal of …, 2019 - mdpi.com
The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …
to biomaterial implantation, despite the robustness of technologies that hold the promise to …
Nutritional modulation of immune function: analysis of evidence, mechanisms, and clinical relevance
D Wu, ED Lewis, M Pae, SN Meydani - Frontiers in immunology, 2019 - frontiersin.org
It is well-established that the nutritional deficiency or inadequacy can impair immune
functions. Growing evidence suggests that for certain nutrients increased intake above …
functions. Growing evidence suggests that for certain nutrients increased intake above …