The Mechanisms of Disease Caused by Acinetobacter baumannii
Acinetobacter baumannii is a Gram negative opportunistic pathogen that has demonstrated
a significant insurgence in the prevalence of infections over recent decades. With only a …
a significant insurgence in the prevalence of infections over recent decades. With only a …
Cytosolic recognition of microbes and pathogens: inflammasomes in action
Infection is a dynamic biological process underpinned by a complex interplay between the
pathogen and the host. Microbes from all domains of life, including bacteria, viruses, fungi …
pathogen and the host. Microbes from all domains of life, including bacteria, viruses, fungi …
Outer membrane vesicles containing OmpA induce mitochondrial fragmentation to promote pathogenesis of Acinetobacter baumannii
V Tiku, EM Kofoed, D Yan, J Kang, M Xu, M Reichelt… - Scientific reports, 2021 - nature.com
Acinetobacter baumannii is a highly antibiotic resistant Gram-negative bacterium that
causes life-threatening infections in humans with a very high mortality rate. A. baumannii is …
causes life-threatening infections in humans with a very high mortality rate. A. baumannii is …
Deciphering the virulence factors, regulation, and immune response to Acinetobacter baumannii infection
A Shadan, A Pathak, Y Ma, R Pathania… - Frontiers in Cellular and …, 2023 - frontiersin.org
Deciphering the virulence factors, regulation, and immune response to Acinetobacter
baumannii infection Acinetobacter baumannii is a gram-negative multidrug-resistant …
baumannii infection Acinetobacter baumannii is a gram-negative multidrug-resistant …
[HTML][HTML] The intracellular life of Acinetobacter baumannii
A Maure, E Robino, C Van der Henst - Trends in Microbiology, 2023 - cell.com
Acinetobacter baumannii is a Gram-negative opportunistic bacterium responsible for
nosocomial and community-acquired infections. This pathogen is globally disseminated and …
nosocomial and community-acquired infections. This pathogen is globally disseminated and …
Host Innate Immune Responses to Acinetobacter baumannii Infection
W Chen - Frontiers in Cellular and Infection Microbiology, 2020 - frontiersin.org
Acinetobacter baumannii has emerged as a major threat to global public health and is one
of the key human pathogens in healthcare (nosocomial and community-acquired) …
of the key human pathogens in healthcare (nosocomial and community-acquired) …
Inhibition of sphingosine-1-phosphate receptor 3 suppresses ATP-induced NLRP3 inflammasome activation in macrophages via TWIK2-mediated potassium efflux
Y Wang, C Wang, Q He, G Chen, J Yu, J Cang… - Frontiers in …, 2023 - frontiersin.org
Background Inhibition of sphingosine kinase 1 (SphK1), which catalyzes bioactive lipid
sphingosine-1–phosphate (S1P), attenuates NLRP3 inflammasome activation. S1P exerts …
sphingosine-1–phosphate (S1P), attenuates NLRP3 inflammasome activation. S1P exerts …
Epithelial pyroptosis in host defense
MJ Churchill, PS Mitchell, I Rauch - Journal of molecular biology, 2022 - Elsevier
Pyroptosis is a lytic form of cell death that is executed by a family of pore-forming proteins
called gasdermins (GSDMs). GSDMs are activated upon proteolysis by host proteases …
called gasdermins (GSDMs). GSDMs are activated upon proteolysis by host proteases …
OmpA Protein-Deficient Acinetobacter baumannii Outer Membrane Vesicles Trigger Reduced Inflammatory Response
J Skerniškytė, E Karazijaitė, A Lučiūnaitė… - Pathogens, 2021 - mdpi.com
Multidrug resistant Acinetobacter baumannii shows a growing number of nosocomial
infections worldwide during the last decade. The outer membrane vesicles (OMVs) …
infections worldwide during the last decade. The outer membrane vesicles (OMVs) …
Virulence Factors and Pathogenicity Mechanisms of Acinetobacter baumannii in Respiratory Infectious Diseases
Y Yao, Q Chen, H Zhou - Antibiotics, 2023 - mdpi.com
Acinetobacter baumannii (A. baumannii) has become a notorious pathogen causing
nosocomial and community-acquired infections, especially ventilator-associated …
nosocomial and community-acquired infections, especially ventilator-associated …