This review summarizes recent evidence on how mid‐life hypertension,
hyperhomocysteinemia (HHcy) and blood pressure variability, as well as late‐life …

Alzheimer's disease (AD) is a complex age-related neurodegenerative disease, associated
with central and peripheral metabolic anomalies, such as impaired glucose utilization and …

Although dysautonomia was documented in inflammatory bowel disease, with activation of
the stress-related sympathetic system, the role of agonists/antagonists of the adrenergic …

In the retina, hypoxic condition leads to overgrowing leaky vessels resulting in altered
metabolic supply that may cause impaired visual function. Hypoxia-inducible factor-1 (HIF-1) …

Alzheimer's disease (AD) is an age-related neurodegenerative disorder, characterized by
the accumulation of proteinaceous aggregates and neurofibrillary lesions composed of β …

Adipose tissue undergoes significant changes in structure, composition, and function with
age including altered adipokine secretion, decreased adipogenesis, altered immune cell …

High dietary intake of saturated fatty acids is a suspected risk factor for neurodegenerative
diseases, including Alzheimer's disease (AD). To decipher the causal link behind these …

Norepinephrine plays an important role in modulating memory through its beta-adrenergic
receptors (Adrβ: β1, β2 and β3). Here, we hypothesized that multisensory stimulation would …

Oxygen level is a key regulator of organogenesis and its modification in postnatal life alters
the maturation process of organs, including the intestine, which do not completely develop in …

In Alzheimer's disease (AD), hyper-phosphorylation and aggregation of tau correlate with
clinical progression and represent a valid therapeutic target. A recent 20-year prospective …