Chronic obstructive pulmonary disease (COPD) is a major incurable global health burden
and is currently the 4th largest cause of death in the world. Importantly, much of the disease …

The ongoing COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. Age,
smoking, obesity, and chronic diseases such as cardiovascular disease and diabetes have …

With the worldwide obesity epidemic, the proportion of women entering pregnancy
overweight or obese has increased significantly in recent years. Babies born to obese …

Prior to statistical analysis of mass spectrometry (MS) data, quality control (QC) of the
identified biomolecule peak intensities is imperative for reducing process-based sources of …

Endoplasmic reticulum (ER) stress mediates the effects of obesity on aggravating sepsis-
induced lung injury. We investigated whether exosomes from human placenta …

Chronic intake of Western diet has driven an epidemic of obesity and metabolic syndrome,
but how it induces mortality remains unclear. Here, we show that chronic intake of a high-fat …

We have shown that obesity-associated attenuation of murine acute lung injury is driven, in
part, by blunted neutrophil chemotaxis, yet differences were noted between the two models …

As the capability of mass spectrometry-based proteomics has matured, tens of thousands of
peptides can be measured simultaneously, which has the benefit of offering a systems view …

Aims The inflammatory response in acute lung injury/acute respiratory distress syndrome
(ALI/ARDS) is heightened in obesity. The aim of this study was to investigate whether …

Introduction Chronic nicotine exposure induces changes in the expression of key regulatory
genes associated with metabolic function and neuronal alterations in the brain. Many …