[HTML][HTML] Red risks for a journey to the red planet: The highest priority human health risks for a mission to Mars

ZS Patel, TJ Brunstetter, WJ Tarver, AM Whitmire… - npj …, 2020 - nature.com
NASA's plans for space exploration include a return to the Moon to stay—boots back on the
lunar surface with an orbital outpost. This station will be a launch point for voyages to …

Use of actigraphy for the evaluation of sleep disorders and circadian rhythm sleep-wake disorders: an American Academy of Sleep Medicine systematic review, meta …

MT Smith, CS McCrae, J Cheung, JL Martin… - Journal of clinical …, 2018 - jcsm.aasm.org
Introduction: The purpose of this systematic review is to provide supporting evidence for a
clinical practice guideline on the use of actigraphy. Methods: The American Academy of …

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight

FE Garrett-Bakelman, M Darshi, SJ Green, RC Gur… - Science, 2019 - science.org
INTRODUCTION To date, 559 humans have been flown into space, but long-duration (> 300
days) missions are rare (n= 8 total). Long-duration missions that will take humans to Mars …

[HTML][HTML] Later circadian timing of food intake is associated with increased body fat

AW McHill, AJK Phillips, CA Czeisler, L Keating… - The American journal of …, 2017 - Elsevier
Background Weight gain and obesity have reached alarming levels. Eating at a later clock
hour is a newly described risk factor for adverse metabolic health; yet, how eating at a later …

[HTML][HTML] Immune system dysregulation during spaceflight: potential countermeasures for deep space exploration missions

BE Crucian, A Choukèr, RJ Simpson, S Mehta… - Frontiers in …, 2018 - frontiersin.org
Recent studies have established that dysregulation of the human immune system and the
reactivation of latent herpesviruses persists for the duration of a 6-month orbital spaceflight …

The effect of prolonged spaceflight on cerebrospinal fluid and perivascular spaces of astronauts and cosmonauts

G Barisano, F Sepehrband… - Proceedings of the …, 2022 - National Acad Sciences
Long-duration spaceflight induces changes to the brain and cerebrospinal fluid
compartments and visual acuity problems known as spaceflight-associated neuro-ocular …

[HTML][HTML] Human health during space travel: state-of-the-art review

C Krittanawong, NK Singh, RA Scheuring, E Urquieta… - Cells, 2022 - mdpi.com
The field of human space travel is in the midst of a dramatic revolution. Upcoming missions
are looking to push the boundaries of space travel, with plans to travel for longer distances …

An overview of space medicine

PD Hodkinson, RA Anderton… - BJA: British Journal of …, 2017 - academic.oup.com
Abstract Space medicine is fundamental to the human exploration of space. It supports
survival, function and performance in this challenging and potentially lethal environment. It is …

[HTML][HTML] Astronaut omics and the impact of space on the human body at scale

LA Rutter, H Cope, MJ MacKay, R Herranz… - Nature …, 2024 - nature.com
Future multi-year crewed planetary missions will motivate advances in aerospace nutrition
and telehealth. On Earth, the Human Cell Atlas project aims to spatially map all cell types in …

[HTML][HTML] Long-term human spaceflight and inflammaging: Does it promote aging?

M Capri, M Conte, E Ciurca, C Pirazzini… - Ageing Research …, 2023 - Elsevier
Spaceflight and its associated stressors, such as microgravity, radiation exposure,
confinement, circadian derailment and disruptive workloads represent an unprecedented …