The yellow polyphenolic pigment known as curcumin, originating from the rhizome of the
turmeric plant Curcuma longa L., has been utilized for ages in ancient medicine, as well as …

Sarcopenia is an age‐related muscle disorder typically associated with a poor quality of life.
Its definition has evolved over time, and several underlying causes of sarcopenia in the …

The amyloid aggregation of α-synuclein (α-Syn) is highly associated with Parkinson's
disease (PD). Discovering α-Syn amyloid inhibitors is one of the strategies for PD therapies …

Microvascular complications are responsible for a major proportion of the burden associated
with diabetes contributing to substantial morbidity, mortality, and healthcare burden in …

Self-assembly of misfolded proteins into ordered fibrillar aggregates known as amyloid
results in various human diseases. However, more and more proteins, whether in human …

The aggregation of α‐synuclein (α‐Syn) is a critical pathological hallmark of Parkinson's
disease (PD). Prevention of α‐Syn aggregation has become a key strategy for treating PD …

There are currently no standardized therapies for Parkinson disease (PD). Curcumin shows
anti-amyloidogenic properties in vitro and may be a promising treatment for PD. We …

Abnormal accumulation of misfolded proteins in the endoplasmic reticulum and their
aggregation causes inflammation and endoplasmic reticulum stress. This promotes …

Inhibition of fibril formation is considered a possible treatment strategy for amyloid-related
diseases. Understanding the molecular nature of inhibitor action is crucial for the design of …

Background Aging refers to a comprehensive manifestation of decreased functions and
physical disorders during the degenerative period. Autophagy can remove damaged …