Solid dispersion formulations by FDM 3D printing—A review

GM Khalid, N Billa - Pharmaceutics, 2022 - mdpi.com
Additive manufacturing (AM) is revolutionizing the way medicines are designed,
manufactured, and utilized. Perhaps, AM appears to be ideal for the fit-for-purpose …

Optimizing solvent selection and processing conditions to generate high bulk-density, co-precipitated amorphous dispersions of posaconazole

D Frank, L Schenck, A Koynov, Y Su, Y Li… - Pharmaceutics, 2021 - mdpi.com
Co-precipitation is an emerging method to generate amorphous solid dispersions (ASDs),
notable for its ability to enable the production of ASDs containing pharmaceuticals with …

Use of surfactant-based amorphous solid dispersions for BDDCS class II drugs to enhance oral bioavailability: A case report of resveratrol

X Jia, J Chen, H Cheng, X Pan, Y Ke, T Fu… - International Journal of …, 2023 - Elsevier
This paper aimed to improve in vitro dissolution/solubility as well as inhibit intestinal
metabolism and thus enhance oral bioavailability for a BDDCS class II drug by constructing …

Formulation of a 3D Printed Biopharmaceutical: The Development of an Alkaline Phosphatase Containing Tablet with Ileo-Colonic Release Profile to Treat Ulcerative …

KTT Nguyen, FFM Heijningen, D Zillen… - Pharmaceutics, 2022 - mdpi.com
Powder bed printing is a 3D-printing process that creates freeform geometries from powders,
with increasing traction for personalized medicine potential. Little is known about its …

[HTML][HTML] The Value of Bead Coating in the Manufacturing of Amorphous Solid Dispersions: A Comparative Evaluation with Spray Drying

E Boel, F Reniers, W Dehaen, G Van den Mooter - Pharmaceutics, 2022 - mdpi.com
Despite the fact that an amorphous solid dispersion (ASD)-coated pellet formulation offers
potential advantages regarding the minimization of physical stability issues, there is still a …

Gaining insight into the role of the solvent during spray drying of amorphous solid dispersions by studying evaporation kinetics

S Dedroog, P Adriaensens… - Molecular …, 2022 - ACS Publications
Spray drying is one of the most commonly used manufacturing techniques for amorphous
solid dispersions (ASDs). During spray drying, very fast solvent evaporation is enabled by …

[HTML][HTML] Novel cationic cellulose beads for oral delivery of poorly water-soluble drugs

F Xie, J Slak, P Fardim, G Van den Mooter - International Journal of …, 2023 - Elsevier
Cellulose beads emerge as carriers for poorly water-soluble drugs due to their eco-friendly
raw materials and favorable porous structure. However, drug dissolution may be limited by …

Stabilization and delivery of therapeutic proteins in the solid state: toward a better shelf-life and personalized treatment with targeted delivery

TTK Nguyễn - 2024 - research.rug.nl
Research towards the stability and the delivery of therapeutic proteins in the solid state and
are the main subjects of this thesis. Firstly, we reviewed component distribution in the solid …

[PDF][PDF] Fan Xie

F Kiekens - lirias.kuleuven.be
Controlled drug delivery systems that can precisely release drugs to specific sites in the
human gastrointestinal tract (GIT) at a specific rate have unparalleled advantages compared …

[引用][C] Influence of formulation and process parameters on the kinetic stabilization of amorphous solid dispersions with high drug loading

S Dedroog - 2022