Optimizing solvent selection and processing conditions to generate high bulk-density, co-precipitated amorphous dispersions of posaconazole
Co-precipitation is an emerging method to generate amorphous solid dispersions (ASDs),
notable for its ability to enable the production of ASDs containing pharmaceuticals with …
notable for its ability to enable the production of ASDs containing pharmaceuticals with …
Use of surfactant-based amorphous solid dispersions for BDDCS class II drugs to enhance oral bioavailability: A case report of resveratrol
X Jia, J Chen, H Cheng, X Pan, Y Ke, T Fu… - International Journal of …, 2023 - Elsevier
This paper aimed to improve in vitro dissolution/solubility as well as inhibit intestinal
metabolism and thus enhance oral bioavailability for a BDDCS class II drug by constructing …
metabolism and thus enhance oral bioavailability for a BDDCS class II drug by constructing …
Formulation of a 3D Printed Biopharmaceutical: The Development of an Alkaline Phosphatase Containing Tablet with Ileo-Colonic Release Profile to Treat Ulcerative …
KTT Nguyen, FFM Heijningen, D Zillen… - Pharmaceutics, 2022 - mdpi.com
Powder bed printing is a 3D-printing process that creates freeform geometries from powders,
with increasing traction for personalized medicine potential. Little is known about its …
with increasing traction for personalized medicine potential. Little is known about its …
[HTML][HTML] The Value of Bead Coating in the Manufacturing of Amorphous Solid Dispersions: A Comparative Evaluation with Spray Drying
E Boel, F Reniers, W Dehaen, G Van den Mooter - Pharmaceutics, 2022 - mdpi.com
Despite the fact that an amorphous solid dispersion (ASD)-coated pellet formulation offers
potential advantages regarding the minimization of physical stability issues, there is still a …
potential advantages regarding the minimization of physical stability issues, there is still a …
Gaining insight into the role of the solvent during spray drying of amorphous solid dispersions by studying evaporation kinetics
S Dedroog, P Adriaensens… - Molecular …, 2022 - ACS Publications
Spray drying is one of the most commonly used manufacturing techniques for amorphous
solid dispersions (ASDs). During spray drying, very fast solvent evaporation is enabled by …
solid dispersions (ASDs). During spray drying, very fast solvent evaporation is enabled by …
[HTML][HTML] Novel cationic cellulose beads for oral delivery of poorly water-soluble drugs
F Xie, J Slak, P Fardim, G Van den Mooter - International Journal of …, 2023 - Elsevier
Cellulose beads emerge as carriers for poorly water-soluble drugs due to their eco-friendly
raw materials and favorable porous structure. However, drug dissolution may be limited by …
raw materials and favorable porous structure. However, drug dissolution may be limited by …
Stabilization and delivery of therapeutic proteins in the solid state: toward a better shelf-life and personalized treatment with targeted delivery
TTK Nguyễn - 2024 - research.rug.nl
Research towards the stability and the delivery of therapeutic proteins in the solid state and
are the main subjects of this thesis. Firstly, we reviewed component distribution in the solid …
are the main subjects of this thesis. Firstly, we reviewed component distribution in the solid …