[HTML][HTML] Therapeutic strategies for COVID-19: progress and lessons learned
G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
[HTML][HTML] Structural biology of SARS-CoV-2: open the door for novel therapies
W Yan, Y Zheng, X Zeng, B He, W Cheng - Signal Transduction and …, 2022 - nature.com
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …
[HTML][HTML] A phase 2 trial of the effect of antiandrogen therapy on COVID-19 outcome: no evidence of benefit, supported by epidemiology and in vitro data
K Welen, E Rosendal, M Gisslen, A Lenman, E Freyhult… - European urology, 2022 - Elsevier
Background Men are more severely affected by COVID-19. Testosterone may influence
SARS-CoV-2 infection and the immune response. Objective To clinically, epidemiologically …
SARS-CoV-2 infection and the immune response. Objective To clinically, epidemiologically …
[HTML][HTML] Coronavirus infection and cholesterol metabolism
J Dai, H Wang, Y Liao, L Tan, Y Sun, C Song… - Frontiers in …, 2022 - frontiersin.org
Host cholesterol metabolism remodeling is significantly associated with the spread of human
pathogenic coronaviruses, suggesting virus-host relationships could be affected by …
pathogenic coronaviruses, suggesting virus-host relationships could be affected by …
[HTML][HTML] Circulating microRNAs as emerging regulators of COVID-19
Y Liang, D Fang, X Gao, X Deng, N Chen, J Wu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19), an infectious disease caused by the novel
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global pandemic that …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global pandemic that …
[HTML][HTML] Sexual dimorphism in COVID-19: potential clinical and public health implications
Current evidence suggests that severity and mortality of COVID-19 is higher in men than in
women, whereas women might be at increased risk of COVID-19 reinfection and …
women, whereas women might be at increased risk of COVID-19 reinfection and …
PM2. 5 promotes lung cancer progression through activation of the AhR‐TMPRSS2‐IL18 pathway
TH Wang, KY Huang, CC Chen, YH Chang… - EMBO molecular …, 2023 - embopress.org
Abstract Particulate matter 2.5 (PM2. 5) is a risk factor for lung cancer. In this study, we
investigated the molecular mechanisms of PM2. 5 exposure on lung cancer progression. We …
investigated the molecular mechanisms of PM2. 5 exposure on lung cancer progression. We …
The immune response to COVID‐19: Does sex matter?
Abstract The coronavirus disease 2019 (COVID‐19) pandemic has created unprecedented
challenges worldwide. Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) …
challenges worldwide. Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) …
[HTML][HTML] Sex hormones in SARS-CoV-2 susceptibility: key players or confounders?
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has a clear sex
disparity in clinical outcomes. Hence, the interaction between sex hormones, virus entry …
disparity in clinical outcomes. Hence, the interaction between sex hormones, virus entry …
[HTML][HTML] Are sex hormones promising candidates to explain sex disparities in the COVID-19 pandemic?
ML Brandi - Reviews in Endocrine and Metabolic Disorders, 2022 - Springer
Emerging evidence suggests that the novel Coronavirus disease-2019 (COVID-19) is
deadlier for men than women both in China and in Europe. Male sex is a risk factor for …
deadlier for men than women both in China and in Europe. Male sex is a risk factor for …