Aspergillus fumigatus and Aspergillosis in 2019

JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Fungal infections in hematopoietic stem-cell transplant patients: a review of epidemiology, diagnosis, and management

MS Rahi, V Jindal, P Pednekar… - Therapeutic …, 2021 - journals.sagepub.com
The advent of bone marrow transplant has opened doors to a different approach and offered
a new treatment modality for various hematopoietic stem-cell-related disorders. Since the …

CAR T cells targeting Aspergillus fumigatus are effective at treating invasive pulmonary aspergillosis in preclinical models

M Seif, TK Kakoschke, F Ebel, MM Bellet… - Science Translational …, 2022 - science.org
Aspergillus fumigatus is a ubiquitous mold that can cause severe infections in
immunocompromised patients, typically manifesting as invasive pulmonary aspergillosis …

Aspergillus fumigatus pan-genome analysis identifies genetic variants associated with human infection

AE Barber, T Sae-Ong, K Kang, B Seelbinder, J Li… - Nature …, 2021 - nature.com
Aspergillus fumigatus is an environmental saprobe and opportunistic human fungal
pathogen. Despite an estimated annual occurrence of more than 300,000 cases of invasive …

Hematopoietic cell transplantation-associated thrombotic microangiopathy: a review of pathophysiology, diagnosis, and treatment

J Rosenthal - Journal of blood medicine, 2016 - Taylor & Francis
Transplant-associated thrombotic microangiopathy (TA-TMA) is a multifactorial disorder
caused by systemic vascular endothelial injury that can be triggered by several mechanisms …

[HTML][HTML] Risk factors, prevalence, and outcomes of invasive fungal disease post hematopoietic cell transplantation and cellular therapies: A retrospective monocenter …

E Gavriilaki, P Dolgyras, S Dimou-Mpesikli… - Cancers, 2023 - mdpi.com
Simple Summary Invasive fungal infections (IFD) are a significant cause of morbidity and
mortality in patients with hematological malignant disorders. The aim of this retrospective …

Surveillance for azoles resistance in Aspergillus spp. highlights a high number of amphotericin B‐resistant isolates

F Reichert‐Lima, L Lyra, L Pontes, ML Moretti… - Mycoses, 2018 - Wiley Online Library
Aspergillus spp. are the most common invasive mould infection and are responsible for high
mortality. Aspergillus fumigatus is currently of interest because resistance to azole …

[HTML][HTML] Noncanonical fungal autophagy inhibits inflammation in response to IFN-γ via DAPK1

V Oikonomou, S Moretti, G Renga, C Galosi, M Borghi… - Cell Host & Microbe, 2016 - cell.com
Defects in a form of noncanonical autophagy, known as LC3-associated phagocytosis
(LAP), lead to increased inflammatory pathology during fungal infection. Although LAP …

[PDF][PDF] Inherited cardiomyopathies: A review and pooled analysis of pathophysiology, diagnosis and clinical management

A Albakri - Intern. Med. Care, 2019 - pdfs.semanticscholar.org
Inherited cardiomyopathies (CMs) are a major cause of heart diseases in all age groups,
which severely burdens patients as well as their family members. Data from the past two …

[HTML][HTML] Mainly post-transplant factors are associated with invasive aspergillosis after allogeneic stem cell transplantation: a study from the Surveillance des …

C Robin, C Cordonnier, K Sitbon, N Raus… - Biology of Blood and …, 2019 - Elsevier
Invasive aspergillosis (IA) occurs in up to 23% of allogeneic hematopoietic stem cell
transplantation (HSCT) patients. Although transplant procedures have changed over time …