American Heart Association/American College of Cardiology foundation guide to warfarin therapy

J Hirsh, V Fuster, J Ansell, JL Halperin - Circulation, 2003 - Am Heart Assoc
rin. 25, 26 Inhibition of S-warfarin metabolism is more important clinically because this
isomer is 5 times more potent than the R-isomer as a vitamin K antagonist. 25, 26 …

Epidemiology and pathophysiology of nephrotic syndrome–associated thromboembolic disease

BA Kerlin, R Ayoob, WE Smoyer - Clinical Journal of the American …, 2012 - journals.lww.com
After infections, thromboembolism is considered by many experts to be the most significant
life-threatening complication of nephrotic syndrome. The purpose of this review is to …

Deep vein thrombosis: a clinical review

E Kesieme, C Kesieme, N Jebbin, E Irekpita… - Journal of blood …, 2011 - Taylor & Francis
Background: Deep vein thrombosis (DVT) is the formation of blood clots (thrombi) in the
deep veins. It commonly affects the deep leg veins (such as the calf veins, femoral vein, or …

D-dimer levels and risk of recurrent venous thromboembolism

S Eichinger, E Minar, C Bialonczyk, M Hirschl… - Jama, 2003 - jamanetwork.com
ContextWidespread screening of patients with venous thromboembolism (VTE) for
thrombophilic risk factors has become common clinical practice. Because of the increasing …

3′ end mRNA processing: molecular mechanisms and implications for health and disease

S Danckwardt, MW Hentze, AE Kulozik - The EMBO journal, 2008 - embopress.org
Recent advances in the understanding of the molecular mechanism of mRNA 3′ end
processing have uncovered a previously unanticipated integrated network of transcriptional …

Coagulation, inflammation, and apoptosis: different roles for protein S and the protein S–C4b binding protein complex

SM Rezende, RE Simmonds, DA Lane - Blood, 2004 - ashpublications.org
Protein S (PS) has an established role as an important cofactor to activated protein C (APC)
in the degradation of coagulation cofactors Va and VIIIa. This anticoagulant role is evident …

D‐dimer concentration increases with age reducing the clinical value of the D‐dimer assay in the elderly

PL Harper, E Theakston, J Ahmed… - Internal medicine …, 2007 - Wiley Online Library
Background: The D‐dimer assay is used as an exclusion test in the assessment of
suspected venous thromboembolic disease; patients with a negative result have a low …

[HTML][HTML] Deep vein thrombosis associated with central venous catheters–a review

CJ van Rooden, MET Tesselaar, S Osanto… - Journal of Thrombosis …, 2005 - Elsevier
Central venous catheters (CVCs) are frequently used in patients for a variety of indications
such as cancer treatment, diagnostic monitoring, parenteral nutrition, hemodialysis, cardiac …

Comparison of 10-mg and 5-mg warfarin initiation nomograms together with low-molecular-weight heparin for outpatient treatment of acute venous thromboembolism …

MJ Kovacs, M Rodger, DR Anderson… - Annals of Internal …, 2003 - acpjournals.org
Background: The optimal means of achieving therapeutic oral anticoagulation in the
outpatient setting has not been determined. Objective: To compare a 10-mg dosing …

[HTML][HTML] Deep vein thrombosis in cancer: the scale of the problem and approaches to management

A Falanga, L Zacharski - Annals of Oncology, 2005 - Elsevier
Patients with cancer have long been recognised to be at high risk of venous
thromboembolism (VTE), although the condition remains under diagnosed and under …