[HTML][HTML] Monkeypox: epidemiology, pathogenesis, treatment and prevention

Y Huang, L Mu, W Wang - Signal Transduction and Targeted Therapy, 2022 - nature.com
Monkeypox is a zoonotic disease that was once endemic in west and central Africa caused
by monkeypox virus. However, cases recently have been confirmed in many nonendemic …

Monkeypox virus infections in humans

S Elsayed, L Bondy, WP Hanage - Clinical microbiology reviews, 2022 - Am Soc Microbiol
Human monkeypox is a viral zoonosis endemic to West and Central Africa that has recently
generated increased interest and concern on a global scale as an emerging infectious …

[HTML][HTML] Interim clinical treatment considerations for severe manifestations of mpox—United States, February 2023

AK Rao - MMWR. Morbidity and Mortality Weekly Report, 2023 - cdc.gov
Data relevant to the use of tecovirimat, brincidofovir, cidofovir, trifluridine ophthalmic
solution, and vaccinia immune globulin intravenous were reviewed. Animal models, MCM …

The land-scape of immune response to monkeypox virus

H Li, QZ Huang, H Zhang, ZX Liu, XH Chen, LL Ye… - …, 2023 - thelancet.com
Human monkeypox is a viral zoonotic smallpox-like disease caused by the monkeypox virus
(MPXV) and has become the greatest public health threat in the genus Orthopoxvirus after …

Tecovirimat for the treatment of human monkeypox: an initial series from Massachusetts, United States

WR Matias, JM Koshy, EH Nagami… - Open forum …, 2022 - academic.oup.com
A large, ongoing multicountry outbreak of human monkeypox has the potential to cause
considerable morbidity and mortality. Therapeutics for the treatment of smallpox, a related …

Combating emerging viral threats

E Bekerman, S Einav - Science, 2015 - science.org
Although hundreds of viruses are known to cause human disease, antiviral therapies are
approved for fewer than 10. Most approved antiviral drugs target viral enzymes, most …

The cumulative burden of double-stranded DNA virus detection after allogeneic HCT is associated with increased mortality

JA Hill, BT Mayer, H Xie, WM Leisenring… - Blood, The Journal …, 2017 - ashpublications.org
Strategies to prevent active infection with certain double-stranded DNA (dsDNA) viruses
after allogeneic hematopoietic cell transplantation (HCT) are limited by incomplete …

An old acquaintance: could adenoviruses be our next pandemic threat?

G Saint-Pierre Contreras, D Conei Valencia, L Lizama… - viruses, 2023 - mdpi.com
Human adenoviruses (HAdV) are one of the most important pathogens detected in acute
respiratory diseases in pediatrics and immunocompromised patients. In 1953, Wallace …

Phosphonate prodrugs: an overview and recent advances

KM Heidel, CS Dowd - Future medicinal chemistry, 2019 - Taylor & Francis
Phosphonates, often used as isosteric replacements for phosphates, can provide important
interactions with an enzyme. Due to their high charge at physiological pH, however …

Adenovirus in solid organ transplant recipients: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice

DF Florescu, JM Schaenman… - Clinical …, 2019 - Wiley Online Library
These updated guidelines from the Infectious Diseases Community of Practice of the
American Society of Transplantation review the diagnosis, prevention, and management of …