Asthma: a syndrome composed of heterogeneous diseases

L Borish, JA Culp - Annals of Allergy, Asthma & Immunology, 2008 - Elsevier
OBJECTIVE: To review the concept that asthma comprises distinct heterogeneous
inflammatory disorders characterized by patients showing different phenotypes with distinct …

Update on gene modifiers in cystic fibrosis

JM Collaco, GR Cutting - Current opinion in pulmonary medicine, 2008 - journals.lww.com
Several genes have been demonstrated to affect disease severity in CF. Furthermore, it is
likely that gene–gene and gene–environment interactions can explain a substantial portion …

[HTML][HTML] TET1 contributes to allergic airway inflammation and regulates interferon and aryl hydrocarbon receptor signaling pathways in bronchial epithelial cells

JD Burleson, D Siniard, VK Yadagiri, X Chen… - Scientific reports, 2019 - nature.com
Previous studies have suggested a role for Tet1 in the pathogenesis of childhood asthma.
However, how Tet1 contributes to asthma remains unknown. Here we used mice deficient …

Asthma in childhood

PD Robinson, P Van Asperen - Pediatric Clinics of North America, 2009 - Elsevier
Management decisions for pediatric asthma (in patients younger than 12 years of age)
based on extrapolation from available evidence in adolescents and adults (age 12 years …

Racial differences in attitudes toward personalized medicine

VA Diaz, AG Mainous Iii, JK Gavin, D Wilson - Public Health Genomics, 2014 - karger.com
Abstract Background/Aims: Patient concerns regarding personalized medicine may limit its
use. This study assesses racial differences in attitudes toward personalized medicine …

Can vaccines interact with drug metabolism?

P Pellegrino, E Clementi, A Capuano… - Pharmacological Research, 2015 - Elsevier
Vaccines are safe and efficacious in reducing the burden of several serious infections
affecting children and adults. Due to their efficacy, vaccines are often administered in …

Asthma 2008: targeting immunoglobulin E to achieve disease control

BM Prenner - Journal of Asthma, 2008 - Taylor & Francis
Traditionally, practice guidelines have recommended a step-wise approach to treatment
based on asthma severity and lung function. However, increasing evidence suggests that …

糖皮质激素治疗儿童急性肺损伤/急性呼吸窘迫综合征的研究进展

王莹 - 国际儿科学杂志, 2010 - cqvip.com
儿童急性肺损伤/急性呼吸窘迫综合征(ALI/ARDS) 是许多肺内疾病和(或) 肺外疾病所致的严重应
激反应和(或) 严重炎症反应而导致的肺组织内皮和上皮受损引起的急性呼吸衰竭, 病死率很高 …

[PDF][PDF] 小剂量甲泼尼龙对肺炎支原体肺炎患儿血清肿瘤坏死因子α 水平的影响

贺金娥, 高春燕, 李红日 - 2013 - zgddek.com
目的观察小剂量甲泼尼龙对肺炎支原体肺炎(MPP) 患儿血清肿瘤坏死因子α (TNF-α)
水平的影响. 方法选取2012 年1 月至2012 年12 月患MPP 且住院前均未使用糖皮质激素的38 …

[PDF][PDF] Фармакогенетические аспекты терапевтически резистентной бронхиальной астмы

ЖА Миронова, ВИ Трофимов… - Пульмонология, 2013 - journal.pulmonology.ru
Среди пациентов с БА у 5–20% отмечена ТБА, нередко с рефрактерностью к
традиционной тера пии [3, 7, 8]. Пациенты именно этой группы чаще обращаются за …