Voltage-gated calcium (CaV) channels are ubiquitously expressed in various cell types
throughout the body. In principle, the molecular identity, biophysical profile, and …

The transmission of pain signals at the spinal level is crucially dependent on voltage-gated
Ca 2+ channels in nociceptive neurons. Pharmacological and gene-knockout studies …

Introduction Studies of categorical decision-making attempt to understand behavior by
probing how different features of complex and changing environments guide the selection of …

Spike output in many neuronal cell types is affected by low‐voltage‐activated T‐type
calcium currents arising from the Cav3. 1, Cav3. 2 and Cav3. 3 channel subtypes and their …

Abstract Cadmium (Cd 2+) is a toxic and non-essential divalent metal ion in eukaryotic cells.
Cells can only be targeted by Cd 2+ if it hijacks physiological high-affinity entry pathways …

T-type calcium channels are expressed in many diverse tissues, including neuronal,
cardiovascular, and endocrine. T-type calcium channels are known to play roles in the …

The kidney has recently emerged as an organ with a significant role in systemic iron (Fe)
homeostasis. Substantial amounts of Fe are filtered by the kidney, which have to be …

Low-voltage activated, T-type calcium channels (T-channels) are expressed in many
developing tissues and may be important in regulating important cellular phenotype …

T-type channels are distinguished among voltage-gated Ca2+ channels by their low voltage
thresholds for activation and inactivation, fast inactivation and small single channel …

Calcium (Ca2+) entry in cells is crucial for development and physiology of virtually all cell
types. It acts as an intracellular (second) messenger to regulate a diverse array of cellular …