Immune Responses in Controllers of HIV Infection
AK Kwaa, JN Blankson - Annual Review of Immunology, 2023 - annualreviews.org
Elite controllers are a heterogeneous group of people living with HIV who control viral
replication without antiretroviral therapy. There is substantial evidence that at least some …
replication without antiretroviral therapy. There is substantial evidence that at least some …
The humanized mouse model: what added value does it offer for HIV research?
L Baroncini, S Bredl, KP Nicole, RF Speck - Pathogens, 2023 - mdpi.com
In the early 2000s, novel humanized mouse models based on the transplantation of human
hematopoietic stem and progenitor cells (HSPCs) into immunocompromised mice were …
hematopoietic stem and progenitor cells (HSPCs) into immunocompromised mice were …
[PDF][PDF] An active HIV reservoir during ART is associated with maintenance of HIV-specific CD8+ T cell magnitude and short-lived differentiation status
H Takata, JL Mitchell, J Pacheco, A Pagliuzza… - Cell host & …, 2023 - cell.com
Before initiation of antiretroviral therapy (ART), HIV-specific CD8+ T cells are dysfunctional
and short lived. To better understand the relationship between the HIV reservoir in CD4+ T …
and short lived. To better understand the relationship between the HIV reservoir in CD4+ T …
[HTML][HTML] Generating and measuring effective vaccine-elicited HIV-specific CD8+ T cell responses
GM Borgo, RL Rutishauser - Current Opinion in HIV and AIDS, 2023 - journals.lww.com
Identifying a vaccine capable of generating durable T cell responses that target mutationally
vulnerable epitopes and that can rapidly intercept infecting or rebounding virus remains a …
vulnerable epitopes and that can rapidly intercept infecting or rebounding virus remains a …
Harnessing Autophagy to Overcome Antigen-Specific T-Cell Dysfunction: Implication for People Living with HIV-1
Like other chronic viral infections, HIV-1 persistence inhibits the development of antigen-
specific memory T-cells, resulting in the exhaustion of the immune response and chronic …
specific memory T-cells, resulting in the exhaustion of the immune response and chronic …
Immunomodulatory Effects of Non-Thermal Plasma in a Model for Latent HIV-1 Infection: Implications for an HIV-1-Specific Immunotherapy
In people living with HIV-1 (PLWH), antiretroviral therapy (ART) eventually becomes
necessary to suppress the emergence of human immunodeficiency virus type 1 (HIV-1) …
necessary to suppress the emergence of human immunodeficiency virus type 1 (HIV-1) …
CD8+ cells and small viral reservoirs facilitate post-ART control of SIV replication in M3+ Mauritian cynomolgus macaques initiated on ART two weeks post-infection
OE Harwood, LM Matschke, RV Moriarty… - PLoS …, 2023 - journals.plos.org
Sustainable HIV remission after antiretroviral therapy (ART) withdrawal, or post-treatment
control (PTC), remains a top priority for HIV treatment. We observed surprising PTC in an …
control (PTC), remains a top priority for HIV treatment. We observed surprising PTC in an …
Accelerated CD8+ T cell maturation in infants with perinatal HIV infection
In perinatal HIV infection, early antiretroviral therapy (ART) initiation is recommended but
questions remain regarding infant immune responses to HIV and its impact on immune …
questions remain regarding infant immune responses to HIV and its impact on immune …
Influence of Splenomegaly and Splenectomy on the Immune Cell Profile of Patients with Common Variable Immunodeficiency Disease
JF Viallard, M Parrens, P Blanco, JF Moreau… - Journal of Clinical …, 2024 - Springer
Purpose About 25% of patients with common variable immunodeficiency disease (CVID)
have splenomegaly, necessitating sometimes splenectomy whom consequences on the …
have splenomegaly, necessitating sometimes splenectomy whom consequences on the …
[HTML][HTML] CD8+ cells and small viral reservoirs facilitate post-ART control of SIV in Mauritian cynomolgus macaques
OE Harwood, LM Matschke, RV Moriarty, AJ Balgeman… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Sustainable HIV remission after antiretroviral therapy (ART) withdrawal, or post-treatment
control (PTC), remains a top priority for HIV treatment. We observed surprising PTC in an …
control (PTC), remains a top priority for HIV treatment. We observed surprising PTC in an …