We have conducted a narrative review based on a structured search strategy, focusing on
the effects of metformin on the progression of non-diabetic hyperglycemia to clinical type 2 …

Frailty is a complex syndrome affecting a growing sector of the global population as medical
developments have advanced human mortality rates across the world. Our current …

Background Women have a high risk of frailty independently of age and menopause state.
Diabetes and hypertension increase the risk of frailty and cognitive impairment. Metformin …

Metformin is a widely accepted first-line hypoglycemic agent in current clinical practice, and
it has been applied to the clinic for more than 60 years. Recently, researchers have …

Background With two well‐validated aging measures capturing mortality and morbidity risk,
this study examined whether and to what extent aging mediates the associations of …

With the intensification of population aging worldwide, the health problems of the elderly
have become a particular concern. Functional disability is a prominent problem in the aging …

OBJECTIVE The aim of this study was to describe cross-sectional and longitudinal
associations between glycated hemoglobin (HbA1c) levels and strategies to control type 2 …

Although the public importance of frailty is widely acknowledged by the World Health
Organization, physical frailty is still largely neglected in geriatric mental health care. Firstly in …

Frailty and sarcopenia are frequently observed in patients with end-stage liver disease.
Frailty is a complex condition that arises from deteriorations across various physiological …

Importance Benign prostatic hyperplasia (BPH) in older men can cause lower urinary tract
symptoms (LUTS), which are increasingly managed with medications. Frailty may contribute …