Progress, challenges, and future of nanomedicine

C Zhang, L Yan, X Wang, S Zhu, C Chen, Z Gu, Y Zhao - Nano Today, 2020 - Elsevier
Nanotherapeutics exhibit unique advantages in clinical outcomes compared with
conventional small molecular drugs. The past three decades have seen intensive research …

Controlled drug delivery vehicles for cancer treatment and their performance

S Senapati, AK Mahanta, S Kumar… - Signal transduction and …, 2018 - nature.com
Although conventional chemotherapy has been successful to some extent, the main
drawbacks of chemotherapy are its poor bioavailability, high-dose requirements, adverse …

Thermoresponsive polymer nanocarriers for biomedical applications

A Bordat, T Boissenot, J Nicolas, N Tsapis - Advanced drug delivery …, 2019 - Elsevier
Polymer nanocarriers allow drug encapsulation leading to fragile molecule protection from
early degradation/metabolization, increased solubility of poorly soluble drugs and improved …

Evolution and clinical translation of drug delivery nanomaterials

S Hassan, G Prakash, AB Ozturk, S Saghazadeh… - Nano today, 2017 - Elsevier
With the advent of technology, the role of nanomaterials in medicine has grown
exponentially in the last few decades. The main advantage of such materials has been …

Hyperthermia and temperature-sensitive nanomaterials for spatiotemporal drug delivery to solid tumors

M Amin, W Huang, ALB Seynhaeve, TLM Ten Hagen - Pharmaceutics, 2020 - mdpi.com
Nanotechnology has great capability in formulation, reduction of side effects, and enhancing
pharmacokinetics of chemotherapeutics by designing stable or long circulating nano …

Withania somnifera: Progress towards a Pharmaceutical Agent for Immunomodulation and Cancer Therapeutics

VK Kashyap, G Peasah-Darkwah, A Dhasmana… - Pharmaceutics, 2022 - mdpi.com
Chemotherapy is one of the prime treatment options for cancer. However, the key issues
with traditional chemotherapy are recurrence of cancer, development of resistance to …

Review of the mechanism of nanocarriers and technological developments in the field of nanoparticles for applications in cancer theragnostics

N Shreyash, M Sonker, S Bajpai… - ACS Applied Bio …, 2021 - ACS Publications
Cancer cannot be controlled by the usage of drugs alone, and thus, nanotechnology is an
important technique that can provide the drug with an impetus to act more effectively. There …

Light-responsive micelles loaded with doxorubicin for osteosarcoma suppression

J Chen, C Qian, P Ren, H Yu, X Kong… - Frontiers in …, 2021 - frontiersin.org
The enhancement of tumor targeting and cellular uptake of drugs are significant factors in
maximizing anticancer therapy and minimizing the side effects of chemotherapeutic drugs. A …

Utilizing stimuli responsive linkages to engineer and enhance polymer nanoparticle-based drug delivery platforms

KK Hershberger, AJ Gauger… - ACS Applied Bio …, 2021 - ACS Publications
The devastating nature of cancer continues to be one of the leading causes of death in the
world. Chemotherapy is among the most common forms of cancer treatment but comes with …

Self-Assembled pH-Responsive Polymeric Micelles for Highly Efficient, Noncytotoxic Delivery of Doxorubicin Chemotherapy To Inhibit Macrophage Activation: In Vitro …

ZS Liao, SY Huang, JJ Huang, JK Chen… - …, 2018 - ACS Publications
Self-assembled pH-responsive polymeric micelles, a combination of hydrophilic poly
(ethylene glycol) segments and hydrogen bonding interactions within a biocompatible …