[HTML][HTML] Antidepressive effect of natural products and their derivatives targeting BDNF-TrkB in gut–brain axis

H Liaqat, A Parveen, SY Kim - International journal of molecular sciences, 2022 - mdpi.com
Modern neurological approaches enable detailed studies on the pathophysiology and
treatment of depression. An imbalance in the microbiota–gut–brain axis contributes to the …

[HTML][HTML] A review of the pharmacological action and mechanism of natural plant polysaccharides in depression

YH Yang, CX Li, RB Zhang, Y Shen, XJ Xu… - Frontiers in …, 2024 - frontiersin.org
Depression is a prevalent mental disorder. However, clinical treatment options primarily
based on chemical drugs have demonstrated varying degrees of adverse reactions and …

[HTML][HTML] Measuring tryptophan dynamics using fast scan cyclic voltammetry at carbon fiber microelectrodes with improved sensitivity and selectivity

I Schapira, MR O'Neill, L Russo-Savage, T Narla… - RSC …, 2023 - pubs.rsc.org
Despite the fact that tryptophan (Trp) is an essential amino acid that humans typically obtain
through diet, there are several interesting tryptophan dynamics at play in the body …

[HTML][HTML] Hawaiian Plants with Beneficial Effects on Sleep, Anxiety, and Mood, etc.

P Meesakul, T Shea, SX Wong, Y Kuroki, S Cao - Pharmaceuticals, 2023 - mdpi.com
Diverse chemical messengers are responsible for maintaining homeostasis in the human
body, for example, hormones and neurotransmitters. Various Hawaiian plant species …

[HTML][HTML] A meta-analysis of the effect of multidisciplinary comprehensive care on health-related quality of life and unified Parkinson's Disease rating scale in …

T Li, X Zou, Y Kang, M Sun, X Huang… - Advances in Clinical …, 2023 - advances.umw.edu.pl
Introduction. According to many reports, multidisciplinary comprehensive care alleviates
Parkinson's disease (PD) more frequently than any other standard care, though the results …

[HTML][HTML] Exploring the interplay between running exercises, microbial diversity, and tryptophan metabolism along the microbiota-gut-brain axis

A Vazquez-Medina, N Rodriguez-Trujillo… - Frontiers in …, 2024 - frontiersin.org
The emergent recognition of the gut-brain axis connection has shed light on the role of the
microbiota in modulating the gut-brain axis's functions. Several microbial metabolites, such …

The potential role of Tirzepatide as adjuvant therapy in countering colistin-induced nephro and neurotoxicity in rats via modulation of PI3K/p-Akt/GSK3-β/NF-kB p65 …

NF Hassan, D Ragab, SG Ibrahim… - International …, 2024 - Elsevier
Although colistin has a crucial antibacterial activity in treating multidrug-resistant gram-
negative bacteria strains; it exhibited renal and neuronal toxicities rendering its use a …

[HTML][HTML] Effect of safranal or candesartan on 3-nitropropionicacid-induced biochemical, behavioral and histological alterations in a rat model of Huntington's disease

NI Shehata, DM Abd EL-Salam, RM Hussein, SM Rizk - Plos one, 2023 - journals.plos.org
3-nitropropionic acid (3-NP) is a potent mitochondrial inhibitor mycotoxin. Systemic
administration of 3-NP can induce Huntington's disease (HD)-like symptoms in experimental …

Rice bran extract mitigates depressive-like behavior in dextran sulfate sodium-induced colitis: Involvement of the gut-brain axis and Sirt1 signaling pathway

HM Shendy, SS Mohamed, EA Abd El-Haleim… - Food and Chemical …, 2024 - Elsevier
Inflammatory bowel disease (IBD) patients frequently suffer from depressive disorders as
well. The present study was carried out to explore whether treatment with a standardized …

[HTML][HTML] Molecular Mechanisms of Reelin in the Enteric Nervous System and the Microbiota–Gut–Brain Axis: Implications for Depression and Antidepressant Therapy

CS Halvorson, CL Sánchez-Lafuente… - International Journal of …, 2024 - mdpi.com
Current pharmacological treatments for depression fail to produce adequate remission in a
significant proportion of patients. Increasingly, other systems, such as the microbiome–gut …