The exact pathogenesis of plaque psoriasis remains to be fully determined, but it is thought
to depend on environmental and genetic factors that stimulate dysregulated innate and …

Understanding the causal role of the immune and inflammatory responses in hypertension
has led to questions regarding the links between hypertension and autoimmunity. Immune …

Background Obesity is a significant risk factor for psoriasis and body mass index (BMI)
correlates with disease severity. Objectives To investigate the relationship between obesity …

Inflammation plays a key role in the pathogenesis of a number of chronic inflammatory
systemic diseases (CISDs), including psoriasis, rheumatoid arthritis, systemic lupus …

BACKGROUND: Symptoms of psoriasis can be embarrassing and distressing, and may
increase risk of developing psychiatric disorders in young people. OBJECTIVE: We sought …

Psoriasis is a common chronic inflammatory disease that is associated with serious
comorbidities, including psoriatic arthritis, reduced quality of life, depression, malignancy …

Patients with psoriasis, in particular those requiring systemic treatment, tend to be above
normal weight. Obesity is associated with psoriasis and contributes significantly to the …

The association between psoriasis and risk of major cardiovascular (CV) events (myocardial
infarction, acute coronary syndrome, unstable angina, and stroke) is unclear. A cohort study …

The Canadian Guidelines for the Management of Plaque Psoriasis were reviewed by the
entire National Psoriasis Foundation Medical Board and updated to include newly approved …

BACKGROUND: Ustekinumab has been evaluated in Caucasian patients with psoriasis, but
no studies have been conducted in Asian patients. OBJECTIVE: To assess the efficacy and …