Neural injuries in cerebral malaria patients are a significant cause of morbidity and mortality.
Nevertheless, a comprehensive research approach to study this issue is lacking, so herein …

Bacteria, fungi, viruses, and protozoa are known to infect and induce diseases in the human
central nervous system (CNS). Modeling the mechanisms of interaction between pathogens …

Malaria is caused by Plasmodium infection and remains a serious public health problem
worldwide, despite control efforts. Malaria can progress to severe forms, affecting multiple …

In this era of advanced technology and innovation, infectious diseases still cause significant
morbidity and mortality, which need to be addressed. Despite overwhelming success in the …

Human cerebral malaria (HCM) is a severe complication of Plasmodium falciparum (Pf)
infection that is characterized by capillary occlusions, rupture of the blood-brain barrier …

Over the years, techniques have been developed to culture and assemble neurons, which
brought us closer to creating neuronal circuits that functionally and structurally mimic parts of …

The basic technology of stem cells has been developed and created organoids, which have
established a strong interest in regenerative medicine. Different cell types have been used …

Objectives Individuals with sickle cell disease (SCD) are at severely heightened risk for
cerebrovascular injury and acute cerebrovascular events, including ischemic and …

Microphysiological systems (MPS) are 2D or 3D multicellular constructs able to mimic tissue
microenvironments. The latest models encompass a range of techniques, including co …

Microbial interactions with the blood–brain barrier (BBB) can be highly pathogenic and are
still not well understood. Among these, parasites present complex interactions with the brain …