Emotional disorders and the cerebellum: neurobiological substrates, neuropsychiatry, and therapeutic implications

JD Schmahmann - Handbook of clinical neurology, 2021 - Elsevier
The notion that the cerebellum is devoted exclusively to motor control has been replaced by
a more sophisticated understanding of its role in neurological function, one that includes …

Cognitive-affective functions of the cerebellum

S Rudolph, A Badura, S Lutzu, SS Pathak… - Journal of …, 2023 - Soc Neuroscience
The cerebellum, traditionally associated with motor coordination and balance, also plays a
crucial role in various aspects of higher-order function and dysfunction. Emerging research …

Cognitive, Emotional, and Other Non-motor Symptoms of Spinocerebellar Ataxias

CYR Lin, SH Kuo, P Opal - Current neurology and neuroscience reports, 2024 - Springer
Abstract Purpose of Review Spinocerebellar ataxias (SCAs) are autosomal dominant
degenerative syndromes that present with ataxia and brain stem abnormalities. This review …

Mapping the cerebellar cognitive affective syndrome in patients with chronic cerebellar strokes

A Chirino-Pérez, OR Marrufo-Meléndez… - The Cerebellum, 2022 - Springer
The cerebellar cognitive affective syndrome (CCAS) has been consistently described in
patients with acute/subacute cerebellar injuries. However, studies with chronic patients have …

Cognitive decline is closely associated with ataxia severity in spinocerebellar ataxia type 2: a validation study of the Schmahmann Syndrome Scale

R Rodríguez-Labrada, A Batista-Izquierdo… - The Cerebellum, 2022 - Springer
The cerebellar cognitive affective syndrome scale (CCAS-S) was designed to detect specific
cognitive dysfunctions in cerebellar patients but is scarcely validated in spinocerebellar …

[HTML][HTML] The CCAS-scale in hereditary ataxias: helpful on the group level, particularly in SCA3, but limited in individual patients

A Thieme, J Faber, P Sulzer, K Reetz, I Dogan… - Journal of …, 2022 - Springer
Background A brief bedside test has recently been introduced by Hoche et al.(Brain, 2018)
to screen for the Cerebellar Cognitive Affective Syndrome (CCAS) in patients with cerebellar …

The cerebellar cognitive affective syndrome and the neuropsychiatry of the cerebellum

JD Schmahmann - Handbook of the cerebellum and cerebellar disorders, 2021 - Springer
The traditional teaching that the cerebellum is purely a motor control device no longer
appears to be valid, if indeed it ever was. Current evidence indicates that there is functional …

Translation, cross-cultural adaptation, and validation to Brazilian Portuguese of the cerebellar cognitive affective/Schmahmann syndrome scale

SS de Oliveira Scott, JL Pedroso, VV Elias… - The Cerebellum, 2023 - Springer
Cerebellar cognitive affective syndrome (CCAS) is characterized by deficits in executive
functions, language processing, spatial orientation, and affect regulation in patients with …

Reference values for the Cerebellar Cognitive Affective Syndrome Scale: age and education matter

A Thieme, S Röske, J Faber, P Sulzer, M Minnerop… - Brain, 2021 - academic.oup.com
During recent decades, many studies have yielded evidence for cerebellar involvement in
cognitive, emotional and affective processes besides the well-known cerebellar contribution …

Patient-reported, health economic and psychosocial outcomes in patients with Friedreich ataxia (PROFA): protocol of an observational study using momentary data …

M Buchholz, N Weber, S Borel, S Sayah, F Xie… - BMJ open, 2023 - bmjopen.bmj.com
Introduction Friedreich ataxia (FA) is the most common hereditary ataxia in Europe,
characterised by progressively worsening movement and speech impairments with a typical …