[HTML][HTML] The impact of race and ethnicity in breast cancer—disparities and implications for precision oncology

KA Hirko, G Rocque, E Reasor, A Taye, A Daly… - BMC medicine, 2022 - Springer
Breast cancer is the most commonly diagnosed cancer worldwide and is one of the leading
causes of cancer death. The incidence, pathological features, and clinical outcomes in …

[HTML][HTML] Using breast cancer gene expression signatures in clinical practice: unsolved issues, ongoing trials and future perspectives

R Varnier, C Sajous, S de Talhouet, C Smentek… - Cancers, 2021 - mdpi.com
Simple Summary Gene expression signatures were initially developed to take into account
tumor biology for adjuvant chemotherapy decision and have become a standard option in …

[HTML][HTML] Novel targeted pH-responsive drug delivery systems based on PEGMA-modified bimetallic Prussian blue analogs for breast cancer chemotherapy

Q Chen, X Huang, G Zhang, J Li, Y Liu, X Yan - RSC advances, 2023 - pubs.rsc.org
The development of novel nanoparticle-based drug delivery systems (nano-DDSs) with high
loading capacity, low toxicity, precise targeting, and excellent biocompatibility remains …

[HTML][HTML] Concomitant analyses of intratumoral microbiota and genomic features reveal distinct racial differences in breast cancer

S Parida, S Siddharth, Y Xia, D Sharma - NPJ Breast Cancer, 2023 - nature.com
Racial disparities are most accentuated among Black women as their lifetime risk of breast
cancer incidence is lower than white and Asian women but their breast cancer related …

[HTML][HTML] Outcomes in breast cancer—does ethnicity matter?

YS Yap - ESMO open, 2023 - Elsevier
Ethnic or racial differences in breast cancer (BC) survival outcomes have been reported, but
current data are largely restricted to comparisons between African Americans and non …

[HTML][HTML] The molecular landscape of Asian breast cancers reveals clinically relevant population-specific differences

JW Pan, MMA Zabidi, PS Ng, MY Meng… - Nature …, 2020 - nature.com
Molecular profiling of breast cancer has enabled the development of more robust molecular
prognostic signatures and therapeutic options for breast cancer patients. However, non …

Palbociclib plus exemestane with gonadotropin-releasing hormone agonist versus capecitabine in premenopausal women with hormone receptor-positive, HER2 …

YH Park, TY Kim, GM Kim, SY Kang, IH Park… - The Lancet …, 2019 - thelancet.com
Background Endocrine treatment is recommended by clinical guidelines as the preferred
treatment option for premenopausal as well as postmenopausal women with hormone …

[HTML][HTML] Global burden of female breast cancer: age-period-cohort analysis of incidence trends from 1990 to 2019 and forecasts for 2035

Y Li, J Zheng, Y Deng, X Deng, W Lou, B Wei… - Frontiers in …, 2022 - frontiersin.org
Introduction This study aimed to describe the latest epidemiology of female breast cancer
globally, analyze the change pattern of the incidence rates and the disease's association …

Pembrolizumab Plus Chemotherapy Followed by Pembrolizumab in Patients With Early Triple-Negative Breast Cancer: A Secondary Analysis of a Randomized …

M Takahashi, J Cortés, R Dent, L Pusztai… - JAMA network …, 2023 - jamanetwork.com
Importance In the phase 3 KEYNOTE-522 study, addition of pembrolizumab to neoadjuvant
chemotherapy followed by adjuvant pembrolizumab significantly increased pathologic …

Pembrolizumab plus chemotherapy in Japanese patients with triple‐negative breast cancer: Results from KEYNOTE‐355

M Hattori, N Masuda, T Takano, K Tsugawa… - Cancer …, 2023 - Wiley Online Library
Pembrolizumab plus chemotherapy improved progression‐free survival (PFS) and overall
survival (OS) compared with placebo plus chemotherapy in patients with previously …