Glanzmann thrombasthenia (GT) is an autosomal recessive disorder of platelet aggregation
caused by quantitative or qualitative defects in integrins αIIb and β3. These integrins are …

Platelets play a major role in hemostasis as ppwell as in many other physiological and
pathological processes. Accordingly, production of about 1011 platelet per day as well as …

The inherited platelet glycoprotein deficiencies, Glanzmann thrombasthenia (GT) and
Bernard Soulier syndrome (BSS) are rare but important long‐term bleeding disorders. Once …

Leucocyte adhesion deficiency (LAD) is a rare, innate autosomal recessive
immunodeficiency with three subtypes. Twenty‐nine patients with LADs were diagnosed …

Platelet transfusion is the standard treatment to control or prevent bleeding in patients with
Glanzmann's thrombasthenia (GT), but platelets are often unavailable. Recombinant …

Glanzmann thrombasthenia (GT) is a genetic bleeding disorder characterised by severely
reduced/absent platelet aggregation in response to multiple physiological agonists. The …

Platelets are active key players in haemostasis. Qualitative platelet dysfunctions result in
thrombocytopathies variously characterized by defects of their adhesive and procoagulant …

Glanzmann thrombasthenia (GT) is a rare inherited platelet function disorder caused by a
quantitative and/or qualitative defect of the αIIbβ3 integrin. Pregnancy and delivery are …

Inherited bleeding disorders such as Glanzmann thrombasthenia (GT) lack prophylactic
treatment options. As a result, serious bleeding episodes are treated acutely with blood …

Rare bleeding disorders (RBDs) are a heterogeneous group of coagulation factor
deficiencies that include fibrinogen, prothrombin, α 2-antiplasmin, plasminogen activator …