Simple Summary In this review article, we present the fascinating story of sirolimus
(rapamycin), a drug known to be able to induce fetal hemoglobin, and for this reason of great …

The longevity of grafts remains a major challenge in allogeneic transplantation due to
immune rejection. Systemic immunosuppression can impair graft function and can also …

Heart transplantation (HTx) remains the last therapeutic resort for patients with advanced
heart failure. The present work is a clinically focused review discussing current issues in …

Exploring the nuances of cooperation in public health – a critical reflection on default policies
and reputation effects: a reply to ‘Nurturing, nudging and navigating the increasingly precarious …

Intramyocardial hydrogel injection is a promising therapy to prevent negative remodeling
following myocardial infarction (MI). In this study, we report a mechanism for in-situ gel …

Cellular asymmetry is an important element of efficiency in the compartmentalization of
intracellular chemical reactions that ensure efficient tissue function. Improving the current 3D …

Myocardial infarction (MI) stands out as a highly lethal disease that poses a significant threat
to global health. Worldwide, heart failure resulting from MI remains a leading cause of …

Background. Donation after circulatory death (DCD) heart transplantation (HTx) significantly
expands the donor pool and reduces waitlist mortality. However, high-level evidence-based …

The prevalence of heart failure has increased in the last few decades with an estimate of
over 8 million American to have heart failure by 2030. 1 At the same time, the number of …

Levothyroxine supplementation does not improve heart transplantation from brain-dead
donors | Nature Reviews Cardiology Skip to main content Thank you for visiting nature.com …