[HTML][HTML] Infectious complications of targeted therapies in children with leukemias and lymphomas

I Kyriakidis, E Mantadakis, E Stiakaki, AH Groll… - Cancers, 2022 - mdpi.com
Simple Summary Targeted therapies in children with hematological malignancies moderate
the effects of cytotoxic therapy, thus improving survival rates. They have emerged over the …

[HTML][HTML] Current status and future directions of immunotherapies in soft tissue sarcomas

WGJ Kerrison, ATJ Lee, K Thway, RL Jones, PH Huang - Biomedicines, 2022 - mdpi.com
Immunotherapy in soft tissue sarcoma (STS) has experienced a surge of interest in the past
decade, contributing to an expanding number of therapeutic options for this extremely …

Harnessing immune checkpoint trial data in pediatric cancer

PJ Neeson, PG Ekert - Nature Cancer, 2023 - nature.com
The response rates of pediatric cancers to immune checkpoint inhibitor therapies are
disappointingly low, particularly when compared to the remarkable impact of these drugs in …

[HTML][HTML] Targeting tumor microenvironment and metastasis in children with solid tumors

KM Wessel, RN Kaplan - Current opinion in pediatrics, 2022 - journals.lww.com
Targeting tumor microenvironment and metastasis in children... : Current Opinion in
Pediatrics Targeting tumor microenvironment and metastasis in children with solid tumors …

[HTML][HTML] Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumours

A Nabbi, P Beck, A Delaidelli, DA Oldridge… - Genome Medicine, 2023 - Springer
Background Cancer immunotherapies including immune checkpoint inhibitors and Chimeric
Antigen Receptor (CAR) T-cell therapy have shown variable response rates in paediatric …

Basket trials: from tumour gnostic to tumour agnostic drug development

C Dittrich - Cancer Treatment Reviews, 2020 - Elsevier
Molecular profiling provides the insight that specific genetic alterations can be detected
across a wide range of different histologically characterised tumour types. Thus, the basic …

[HTML][HTML] Novel small 99mTc-labeled affibody molecular probe for PD-L1 receptor imaging

Z Liang, X Hu, H Hu, P Wang, J Cai - Frontiers in oncology, 2022 - frontiersin.org
Objective: In vivo imaging of programmed death ligand 1 (PD-L1) can monitor changes in
PD-L1 expression and target PD-1/PD-L1 therapy. A 99mTc-labeled affibody molecular …

Pediatric adrenocortical neoplasms: a study comparing three histopathological scoring systems

H Jangir, I Ahuja, S Agarwal, V Jain, JP Meena… - Endocrine …, 2023 - Springer
Adrenocortical neoplasms are rare in childhood. Their histopathological categorization into
benign and malignant is often challenging, impacting further management. While the …

[HTML][HTML] Extracranial rhabdoid tumours: results of a SFCE series of patients treated with a dose compression strategy according to European Paediatric Soft tissue …

M Enault, V Minard-Colin, N Corradini… - European Journal of …, 2022 - Elsevier
Background and aims Extracranial malignant rhabdoid tumours are tumours that mainly
affect young children and have a poor prognosis. In 2014, the European Paediatric Soft …

[HTML][HTML] Clinical, genetic, and prognostic features of adrenocortical tumors in children: a 10-year single-center experience

E Miele, A Di Giannatale, A Crocoli, R Cozza… - Frontiers in …, 2020 - frontiersin.org
Background and Aims: Pediatric adrenocortical tumors (ACT) are very rare endocrine
neoplasms in childhood. In this study, we performed a retrospective analysis of children with …