Tissue engineering therapies for the vocal fold lamina propria
JK Kutty, K Webb - Tissue Engineering Part B: Reviews, 2009 - liebertpub.com
The vocal folds are laryngeal connective tissues with complex matrix composition/
organization that provide the viscoelastic mechanical properties required for voice …
organization that provide the viscoelastic mechanical properties required for voice …
[HTML][HTML] In vitro expansion affects the response of chondrocytes to mechanical stimulation
RHJ Das, H Jahr, JAN Verhaar… - Osteoarthritis and …, 2008 - Elsevier
OBJECTIVE: Expansion of autologous chondrocytes is a common step in procedures for
cartilage defect repair. Subsequent dedifferentiation can alter cellular response to …
cartilage defect repair. Subsequent dedifferentiation can alter cellular response to …
Dynamic compression augments interstitial transport of a glucose-like solute in articular cartilage
RC Evans, TM Quinn - Biophysical journal, 2006 - cell.com
Solute transport through the extracellular matrix is essential for cellular activities in articular
cartilage. Increased solute transport via fluid convection may be a mechanism by which …
cartilage. Increased solute transport via fluid convection may be a mechanism by which …
Different mechanical loading protocols influence serum cartilage oligomeric matrix protein levels in young healthy humans
A Niehoff, UG Kersting, S Helling, J Dargel… - European journal of …, 2010 - Springer
The purpose of the study was to investigate whether a relationship between the loading
mode of physical activity and serum cartilage oligomeric matrix protein (COMP) …
mode of physical activity and serum cartilage oligomeric matrix protein (COMP) …
Dynamic compression inhibits the synthesis of nitric oxide and PGE2 by IL-1β-stimulated chondrocytes cultured in agarose constructs
TT Chowdhury, DL Bader, DA Lee - Biochemical and Biophysical Research …, 2001 - Elsevier
Both mechanical loading and interleukin-1β (IL-1β) are known to regulate metabolic
processes in articular cartilage through pathways mediated by nitric oxide (• NO) and PGE2 …
processes in articular cartilage through pathways mediated by nitric oxide (• NO) and PGE2 …
[HTML][HTML] Mitogen-activated protein kinase signaling in bovine articular chondrocytes in response to fluid flow does not require calcium mobilization
In the present study, the role of mitogen-activated protein kinases (MAPKs) in chondrocyte
mechanotransduction was investigated. We hypothesized that MAPKs participate in fluid …
mechanotransduction was investigated. We hypothesized that MAPKs participate in fluid …
Confocal laser scanning microscopy in orthopaedic research
Confocal laser scanning microscopy (CLSM) is a type of high-resolution fluorescence
microscopy that overcomes the limitations of conventional widefield microscopy and …
microscopy that overcomes the limitations of conventional widefield microscopy and …
A Review of the Role of Bioreactors for iPSCs-Based Tissue-Engineered Articular Cartilage
A Reina-Mahecha, MJ Beers, HC van der Veen… - Tissue engineering and …, 2023 - Springer
Background: Osteoarthritis (OA) is the most common degenerative joint disease without an
ultimate treatment. In a search for novel approaches, tissue engineering (TE) has shown …
ultimate treatment. In a search for novel approaches, tissue engineering (TE) has shown …
Local mechanical stimuli correlate with tissue growth in axolotl salamander joint morphogenesis
Movement-induced forces are critical to correct joint formation, but it is unclear how cells
sense and respond to these mechanical cues. To study the role of mechanical stimuli in the …
sense and respond to these mechanical cues. To study the role of mechanical stimuli in the …
Functional tissue engineering of chondral and osteochondral constructs
Due to the prevalence of osteoarthritis (OA) and damage to articular cartilage, coupled with
the poor intrinsic healing capacity of this avascular connective tissue, there is a great …
the poor intrinsic healing capacity of this avascular connective tissue, there is a great …