Our views of the skin immunity theatre are undergoing constant change. These not only
reflect paradigm shifts in general immunology and skin biology, but also have profound …

Selectin enzymes are glycoproteins and are an important adhesion molecule in the
mammalian immune system, especially in the inflammatory response and the healing …

Immune-mediated effector molecules can limit cancer growth, but lack of sustained immune
activation in the tumour microenvironment restricts antitumour immunity. New therapeutic …

Background: Cellular glucose uptake may involve either non-concentrative glucose carriers
of the GLUT family or Na+-coupled glucose-carrier SGLT1, which accumulates glucose …

To better understand the immunopathogenesis of chronic inflammatory lung disease, we
established a mouse model of disease that develops after respiratory viral infection. The …

Based on biological experimental data, we developed a mathematical model of the virus-
triggered signaling pathways that lead to induction of type I IFNs and systematically …

Over the last decades, the interactions between innate and adaptive immunologic
subsystems have been emphasized, in contrast to considering them as 2 separate …

Systemic lupus erythematosus (SLE) is an autoimmune disorder that is characterized by the
development of autoantibodies against nuclear antigens. These autoantibodies and their …

目的观察叉状头/翅膀状螺旋转录因子(Foxp3) 在BXSB 狼疮小鼠肝脏的表达, 探索调节性T
细胞在狼疮肝损害中的可能作用机制. 方法以8 周龄正常C57BL/6 雄性小鼠作对照 …

免疫抑制是控制免疫系统稳定的一种重要机制. 调节性T 细胞(regulatory T cells, Tregs)
控制着免疫系统对自身抗原的免疫耐受, 具有强大的抑制免疫反应能力, 广泛参与了各种免疫 …