[HTML][HTML] Mesenchymal stem cell-derived exosomes and other extracellular vesicles as new remedies in the therapy of inflammatory diseases

CR Harrell, N Jovicic, V Djonov, N Arsenijevic… - Cells, 2019 - mdpi.com
There is growing evidence that mesenchymal stem cell (MSC)-based immunosuppression
was mainly attributed to the effects of MSC-derived extracellular vesicles (MSC-EVs). MSC …

[HTML][HTML] Ethical and safety issues of stem cell-based therapy

V Volarevic, BS Markovic, M Gazdic… - … journal of medical …, 2018 - ncbi.nlm.nih.gov
Results obtained from completed and on-going clinical studies indicate huge therapeutic
potential of stem cell-based therapy in the treatment of degenerative, autoimmune and …

[HTML][HTML] The immunomodulatory functions of mesenchymal stromal/stem cells mediated via paracrine activity

Y Zhou, Y Yamamoto, Z Xiao, T Ochiya - Journal of Clinical Medicine, 2019 - mdpi.com
Mesenchymal stromal/stem cells (MSCs) exist in almost all tissues, possessing the potential
to differentiate into specialized cell types and exert immunomodulatory functions. Thus, they …

Mesenchymal stem cell therapy for the treatment of inflammatory diseases: challenges, opportunities, and future perspectives

S Regmi, S Pathak, JO Kim, CS Yong… - European journal of cell …, 2019 - Elsevier
Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …

Emerging treatments for inflammatory bowel disease

K Hazel, A O'Connor - Therapeutic advances in chronic …, 2020 - journals.sagepub.com
Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis
(UC), is characterized by chronic inflammation, a relapsing and remitting clinical course …

Autologous mesenchymal stem cells improve motor recovery in subacute ischemic stroke: a randomized clinical trial

A Jaillard, M Hommel, A Moisan, TA Zeffiro… - Translational stroke …, 2020 - Springer
While preclinical stroke studies have shown that mesenchymal stem cells (MSCs) promote
recovery, few randomized controlled trials (RCT) have assessed cell therapy in humans. In …

[HTML][HTML] An update on the progress of isolation, culture, storage, and clinical application of human bone marrow mesenchymal stem/stromal cells

DT Chu, TNT Phuong, NLB Tien, DK Tran… - International journal of …, 2020 - mdpi.com
Bone marrow mesenchymal stem/stromal cells (BMSCs), which are known as multipotent
cells, are widely used in the treatment of various diseases via their self-renewable …

[PDF][PDF] Potency analysis of mesenchymal stromal cells using a combinatorial assay matrix approach

R Chinnadurai, D Rajan, M Qayed, D Arafat, M Garcia… - Cell reports, 2018 - cell.com
Assays that can characterize MSC immune potency need to be identified for use in
advanced clinical trials. MSCs possess a number of putative regenerative and …

Mammalian MSC from selected species: Features and applications

C Uder, S Brückner, S Winkler… - Cytometry Part …, 2018 - Wiley Online Library
Mesenchymal stromal/stem cells (MSC) are promising candidates for cellular therapy of
different diseases in humans and in animals. Following the guidelines of the International …

[HTML][HTML] The therapeutic potential of stem cell-derived exosomes in the ulcerative colitis and colorectal cancer

G Guo, Z Tan, Y Liu, F Shi, J She - Stem cell research & therapy, 2022 - Springer
Abstract Background Mesenchymal stem cells (MSCs) therapy is a novel treatment strategy
for cancer and a wide range of diseases with an excessive immune response such as …