Increasing evidence suggests that abnormal cerebral glucose metabolism is largely present
in Alzheimer's disease (AD). The brain utilizes glucose as its main energy source and a …

Aim of the review This study aimed to reveal the classical signal pathways and important
potential targets of traditional Chinese medicine (TCM) for treating Alzheimer's disease (AD) …

Neurodegenerative diseases are growing to become one of humanity's biggest health
problems, given the number of individuals affected by them. They cause enough mortalities …

Sixteen isatin-based hydrazone derivatives (IS1–IS16) were synthesized and assessed for
their ability to inhibit monoamine oxidases (MAOs). All the molecules showed improved …

Intracortical microelectrodes that can record and stimulate brain activity have become a
valuable technique for basic science research and clinical applications. However, long-term …

Postoperative delirium (POD) is common in the elderly and is associated with poor clinical
outcomes. Reactive oxygen species (ROS) and blood-brain barrier (BBB) damage have …

Aim: To investigate whether the estimation of cerebrospinal fluid (CSF) and brain YKL-40
levels may be used as an efficient biomarker for Parkinson's disease (PD). Methods …

Amyloid-beta (Aβ) peptides have a role in the pathogenesis of Alzheimer's disease (AD) and
are thought to promote oxidative stress, endoplasmic reticulum (ER) stress and …

Alzheimer's disease (AD) is a predominantly heterogeneous disease with a highly complex
pathobiology. The presence of amyloid-beta (Aβ) depositions and the accumulation of …

Oxidative stress is involved in the pathogenesis of Alzheimer's disease (AD), which is linked
to reactive oxygen species (ROS), lipid peroxidation, and neurotoxicity. Emerging evidence …