[HTML][HTML] Nanoparticle-mediated combination therapy: two-in-one approach for cancer

S Gurunathan, MH Kang, M Qasim, JH Kim - International journal of …, 2018 - mdpi.com
Cancer represents a group of heterogeneous diseases characterized by uncontrolled
growth and spread of abnormal cells, ultimately leading to death. Nanomedicine plays a …

[HTML][HTML] Molecular targets, therapeutic agents and multitasking nanoparticles to deal with cancer stem cells: A narrative review

A Doustmihan, M Fathi, MA Mazloomi, A Salemi… - Journal of Controlled …, 2023 - Elsevier
There is increasing evidence that malignant tumors are initiated and maintained by a sub-
population of tumor cells that have similar biological properties to normal adult stem cells …

Quercetin and 5-Fu Loaded Chitosan Nanoparticles Trigger Cell-Cycle Arrest and Induce Apoptosis in HCT116 Cells via Modulation of the P53/P21 Axis

S Das, M Saha, LC Mahata, A China, N Chatterjee… - ACS …, 2023 - ACS Publications
Nanoparticles (NPs) are encapsulating agents that exist in the nanometer range. They can
be classified into different classes based on their properties, shapes, or sizes. Metal NPs …

2020 innovation‐based optimism for lung cancer outcomes

EL Schenk, T Patil, J Pacheco, PA Bunn Jr - The oncologist, 2021 - academic.oup.com
Lung cancer is the leading cause of cancer death in both males and females in the US and
worldwide. Owing to advances in prevention, screening/early detection, and therapy, lung …

[HTML][HTML] Identification of gene signature for treatment response to guide precision oncology in clear-cell renal cell carcinoma

NM D'Costa, D Cina, R Shrestha, RH Bell, YY Lin… - Scientific reports, 2020 - nature.com
Clear-cell renal cell carcinoma (ccRCC) is a common therapy resistant disease with
aberrant angiogenic and immunosuppressive features. Patients with metastatic disease are …

Paclitaxel and erlotinib-co-loaded solid lipid core nanocapsules: assessment of physicochemical characteristics and cytotoxicity in non-small cell lung cancer

B Gupta, BK Poudel, S Regmi, S Pathak… - Pharmaceutical …, 2018 - Springer
Purpose Lung cancer is the leading cause of cancer-related deaths. The aim of this study
was to design solid lipid core nanocapsules (SLCN) comprising a solid lipid core and a …

[HTML][HTML] Progression-free survival, response rate, and disease control rate as predictors of overall survival in phase III randomized controlled trials evaluating the first …

K Nakashima, N Horita, K Nagai, S Manabe… - Journal of Thoracic …, 2016 - Elsevier
Introduction Recent improvements in chemotherapy agents have prolonged postprogression
survival of non–small cell lung cancer. Thus, primary outcomes other than overall survival …

Clinical value of miR-145-5p in NSCLC and potential molecular mechanism exploration: A retrospective study based on GEO, qRT-PCR, and TCGA data

T Gan, Z Xie, R Tang, T Zhang, D Li, Z Li… - Tumor …, 2017 - journals.sagepub.com
MicroRNAs have been reported to be involved in various biological processes. Here, we
performed a systematic analysis to explore the clinical value and potential molecular …

Emerging advances in nanomedicine for breast cancer immunotherapy: Opportunities and challenges

MZ Ahmad, AS Alasiri, MY Alasmary, MM Abdullah… - …, 2022 - Taylor & Francis
Breast cancer is one of the most common causes of cancer-related morbidity and mortality in
women worldwide. Early diagnosis and an appropriate therapeutic approach for all cancers …

Evodiamine induces apoptosis and enhances apoptotic effects of erlotinib in wild-type EGFR NSCLC cells via S6K1-mediated Mcl-1 inhibition

Y Li, Y Pan, W Wu, S Mao, J Sun, Y Zhao, J Dong… - Medical oncology, 2016 - Springer
Erlotinib is effective in NSCLC patients with known drug-sensitizing EGFR mutations, but its
clinical efficacy in patients with wild-type EGFR or acquired resistance to erlotinib remains …