Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by a number
of environmental and cell-intrinsic factors to adapt to environmental changes. Accumulating …

Of the neurogenic zones in the adult brain, adult hippocampal neurogenesis attracts the
most attention, because it is involved in higher cognitive function, most notably memory …

Adult neurogenesis in the hippocampus is a notable process due not only to its uniqueness
and potential impact on cognition but also to its localized vertical integration of different …

Adolescence is a developmental period when physical and cognitive abilities are optimized,
when social skills are consolidated, and when sexuality, adolescent behaviors, and frontal …

Degeneration of central cholinergic neurons impairs memory, and enhancement of
cholinergic synapses improves cognitive processes. Cholinergic signaling is also anti …

Alzheimer's disease (AD) is the most common form of dementia affecting the elderly
population today; however, there is currently no accurate description of the etiology of this …

The adult brain is a plastic place. To ensure that the mature nervous system's control of
behaviour is flexible in the face of a varying environment, morphological and physiological …

The generation and cell death of newly generated cells have critical roles in brain
development and maintenance in the embryonic and adult brain. Alterations in these …

Stroke remains the leading cause of long-term disability with limited options available to aid
in recovery. Significant effort has been made to try and minimize neuronal damage following …

Adult hippocampal neurogenesis is an unusual case of brain plasticity, since new neurons
(and not just neurites and synapses) are added to the network in an activity-dependent way …