Major depressive disorder

W Marx, BWJH Penninx, M Solmi… - Nature Reviews …, 2023 - nature.com
Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …

[HTML][HTML] Post-COVID-19 depressive symptoms: epidemiology, pathophysiology, and pharmacological treatment

MG Mazza, M Palladini, S Poletti, F Benedetti - CNS drugs, 2022 - Springer
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic is still spreading worldwide
over 2 years since its outbreak. The psychopathological implications in COVID-19 survivors …

Persistent psychopathology and neurocognitive impairment in COVID-19 survivors: effect of inflammatory biomarkers at three-month follow-up

MG Mazza, M Palladini, R De Lorenzo… - Brain, behavior, and …, 2021 - Elsevier
COVID-19 outbreak is associated with mental health implications during viral infection and
at short-term follow-up. Data on psychiatric and cognitive sequelae at medium-term follow …

COVID-19 pandemic and mental health consequences: Systematic review of the current evidence

N Vindegaard, ME Benros - Brain, behavior, and immunity, 2020 - Elsevier
Background During the COVID-19 pandemic general medical complications have received
the most attention, whereas only few studies address the potential direct effect on mental …

[HTML][HTML] The bidirectional relationship of depression and inflammation: double trouble

E Beurel, M Toups, CB Nemeroff - Neuron, 2020 - cell.com
Depression represents the number one cause of disability worldwide and is often fatal.
Inflammatory processes have been implicated in the pathophysiology of depression. It is …

Comorbid depression in medical diseases

SM Gold, O Köhler-Forsberg, R Moss-Morris… - Nature Reviews …, 2020 - nature.com
Depression is one of the most common comorbidities of many chronic medical diseases
including cancer and cardiovascular, metabolic, inflammatory and neurological disorders …

[HTML][HTML] Immune targets for therapeutic development in depression: towards precision medicine

WC Drevets, GM Wittenberg, ET Bullmore… - Nature reviews Drug …, 2022 - nature.com
Over the past two decades, compelling evidence has emerged indicating that immune
mechanisms can contribute to the pathogenesis of major depressive disorder (MDD) and …

[HTML][HTML] Psychiatric face of COVID-19

L Steardo Jr, L Steardo, A Verkhratsky - Translational psychiatry, 2020 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) represents a severe multiorgan
pathology which, besides cardio-respiratory manifestations, affects the function of the central …

[HTML][HTML] Microglial ERK-NRBP1-CREB-BDNF signaling in sustained antidepressant actions of (R)-ketamine

W Yao, Q Cao, S Luo, L He, C Yang, J Chen, Q Qi… - Molecular …, 2022 - nature.com
Abstract (R, S)-ketamine elicits rapid-acting and sustained antidepressant actions in
treatment-resistant patients with depression.(R)-ketamine produces longer-lasting …

[HTML][HTML] Major depressive disorder: advances in neuroscience research and translational applications

Z Li, M Ruan, J Chen, Y Fang - Neuroscience bulletin, 2021 - Springer
Major depressive disorder (MDD), also referred to as depression, is one of the most common
psychiatric disorders with a high economic burden. The etiology of depression is still not …